From The Labs Archives - Page 57 of 94 - Baylor College of Medicine Blog Network

Solving the mystery of CLN8’s connection with Batten disease

January 24, 2019 Batten disease, CLN8, Lysosomal storage disorder, neuronal ceroid lipofuscinosis 8, Research

Batten disease refers to a group of diseases that are part of the lysosomal storage disorders. At the core of these conditions are problems with

From The Labs

Making ‘sense’ of the ‘cart before the horse’ in mammalian cells

January 22, 2019 antisense RNA, Cancer, fusion DNA, fusion RNA, Prostate Cancer, Research, sense RNA

A fusion gene is a new gene made by joining parts of two different genes. The current thought is that fusion genes can happen in

From The Labs

Connecting Zika virus and hereditary microcephaly

January 17, 2019 ANKLE2, dengue virus, microcephaly, NS4A, Research, Zika virus

Understanding how Zika virus causes microcephaly would hint at possibilities for preventing this irreparable condition in newborns. Heading in that direction, a collaboration between Baylor

From The Labs

When DNA is caught at the break

January 15, 2019 Cancer, DNA fragments, DNA repair, Dna2, immune system, Research

Cells have in place a number of mechanisms to protect the integrity of the genome, including processes that repair mistakes that may occur during DNA

From The Labs

Putting mind and heart together opens a window into the adult brain

January 10, 2019 adult brain, cardiovascular research, olfactory bulb, Research, single cell RNA sequencing

The mammalian brain is a complex tissue composed of diverse cell types. However, despite rapid advances in the field of neuroscience, only a limited number

From The Labs

Mutant PPM1D gives stem cells a survival advantage

January 8, 2019 Cancer, Chemotherapy, clonal hematopoiesis, PPM1D, Research, secondary leukemia

Scroll down to watch the video summary of this work. Although chemotherapy can fight back cancer, it also has been associated with increased risk of

From The Labs

Image of the Month: Assembling a rotavirus factory

January 3, 2019 CK1 alpha, NSP2, phsophorylation, Research, rotavirus, rotavirus factory

Making new viruses requires assembling intracellular replication factories via a complex, little known process that involves both viral and cellular components. New insights into this

From The Labs

Coaching the immune system to delay type 1 diabetes

December 20, 2018 B cells, McNair scholar, Research, type 1 diabetes

In type 1 diabetes, the body does not produce insulin. Without this hormone, cells cannot use sugar in the bloodstream to fuel their activities. In

From The Labs

Baylor College of Medicine faculty members elected fellows of the National Academy of Inventors

December 18, 2018 Alzheimer's, Cancer, NAI, National Academy of Inventors, Norovirus, Research, Rett Syndrome, rotavirus

Drs. Mary K. Estes, Bert O’Malley and Huda Zoghbi of Baylor College of Medicine were three of the 148 renowned academic inventors named fellows of

From The Labs

The power of the microbiome: A microbe-based treatment reverses social deficits in mouse models of autism

December 13, 2018 autism spectrum disorders, L. reuteri, microbial-based treatment, microbiome, Mouse models, Research, social deficits

An unconventional bacteria-based approach has successfully reversed deficits in social behaviors associated with autism spectrum disorders (ASD) in genetic, environmental and idiopathic mouse models of