IQSEC1 gene mutations cause new intellectual disability syndrome
It used to take several years or sometimes decades to unequivocally identify the genes that cause rare human syndromes that affect very few individuals. Nowadays,
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From The Labs
When tau tangles, RNA errors can happen in Alzheimer’s disease
The tau protein is a key player in Alzheimer’s disease. It tangles and accumulates inside brain cells and this, in combination with increasing cell death,
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What the Hippo pathway in cardiac fibroblasts reveals about heart function
Heart failure remains the leading cause of mortality in the U.S. During a heart attack, blood stops flowing into the heart. Without oxygen, part of
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Sox9 reshapes the biliary tree in Alagille syndrome
Alagille syndrome is a rare pediatric genetic disorder that can affect the liver, heart, kidneys, blood vessels, skeleton and other tissues. One major characteristic of
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ON A MATTER OF HEALTH: Clinical trial tests novel treatment strategy for ITP
The immune system is meant to protect the body from foreign invaders. A rare condition called immune thrombocytopenia (ITP) occurs when the body’s defense system
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Exploring the stress-mood-appetite connection
Does stress affect your appetite or your mood? Many people have experienced stressful situations that trigger a particular mood and also change certain feelings toward
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Image of the Month: Islet of Langerhans
Cells of the Islets of Langerhans in the pancreas help regulate blood sugar. Disrupting their normal function can contribute to the development of diabetes. The
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The unexpected functional diversity of reactive astrocytes
When the brain is injured or diseased astrocytes are the first to respond. They become reactive and play roles that can be both beneficial and
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Exploring the risk of ALL in children with Down syndrome
Acute Lymphoblastic Leukemia (ALL) is the most common childhood cancer. Children with trisomy 21 (Down syndrome) are 10 to 20 times more likely to develop ALL
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Early postnatal overnutrition sets the body on a fast track to aging
Overnutrition during early infancy can have adverse health consequences later in life. Although researchers have known this for quite some time, the explanations have been
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