From The Labs Archives - Page 51 of 103 - Baylor College of Medicine Blog Network

The N-terminal domain of the androgen receptor is at the heart of its action

July 30, 2020 androgen receptor, C-terminal domain, coactivators, n-terminal domain, Prostate Cancer, Research, testosterone

Detailed 3-D studies reveal how the androgen receptor is put together as a functional complex that drives prostate cancer.

From The Labs

Taking a closer look into the tumor microenvironment with nano-radiomics

July 28, 2020 cancer treatment, nano-radiomics, research; immunotherapy, tumor microenvironment

Nano-radiomics analysis of imaging data assesses changes in the tumor microenvironment that cannot be detected with conventional imaging methods.

From The Labs

PolyA-miner accurately assesses the effect of alternative polyadenylation on gene expression

July 23, 2020 3′Seq datasets, alternative polyadenylation, gene expression, PolyA-miner, Research

PolyA-miner enables scientists to evaluate the contribution of alternative polyadenylation to gene regulation in health and disease.

From The Labs

New insights into the mediators of patient recovery after CAR T cell immunotherapy

July 21, 2020 cancer therapy, CAR T cell, Clinical Trials, complete response, HER-2, Immunotherapy, Research, rhabdomyosarcoma

Clinical trial of novel personalized CAR T cell immunotherapy provides clues into what mediated exceptional patient recovery.

From The Labs

These 300,000 cells can improve our understanding of chronic lung disease

July 16, 2020 chronic lung disease, chronic obstructive pulmonary disease, online cell atlas, pulmonary fibrosis, Research, RNA sequencing

Researchers create a digital atlas for chronic lung disease.

From The Labs

Sorting out cell type-specific molecular barcodes

July 14, 2020 CluBCpG, DNA methylation, epigenetics, PReLIM, Research, WGBS

Researchers at Baylor College of Medicine developed novel software that can distinguish methylation patterns within bulk WGBS data.

From The Labs

No NELL2, no sperm motility. Novel protein is essential for male fertility

July 9, 2020 lumicrine signaling, male fertility, NELL2, Research, Ros1, sperm motility

An international team of researchers has identified a chain of events that matures the sperm and triggers their motility.

From The Labs

Metabolomics meets genomics to improve patient diagnosis

July 7, 2020 genetic diagnosis, Genomics, metabolomics, Research, undiagnosed disease

Researchers at Baylor College of Medicine have improved their ability to identify the genetic cause of undiagnosed conditions.

From The Labs

Image of the Month: Locating molecular players in Batten disease

July 2, 2020 Batten disease, childhood disease, CLN6, CLN8, Lysosomal storage disorder, neurodevelopmental disorder, Research

Researchers at Baylor College of Medicine discovered how defective protein CLN6 can result in Batten disease.

From The Labs

The single cell and the cluster, what makes one better than the other at cancer metastasis?

June 30, 2020 Breast Cancer, cluster cancer cells, Metastasis, NK cells, Research

Cancer metastasis is all about rogue cancer cells abandoning the original tumor and venturing through the blood in search for new breeding grounds. Sometimes, single