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From The Labs

hnRNPM, a guardian of the integrity of cellular protein synthesis

June 6, 2024 Cancer,  cryptic splicing,  hnRNPM,  Interferon,  protein synthesis,  Pseudo splice sites,  Research

A connection with cancer cells suggests that hnRNPM may hold clinical promise.

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From The Labs

Interferon linked to ER+/HER- metastatic breast cancer resistance to therapy

March 12, 2021 CDK4/6 inhibitor therapy,  endocrine therapy,  ER+/HER2- breast cancer,  Interferon,  Metastatic breast cancer,  Research,  resistance to cancr treatment

Both preclinical models and tumor samples from patients with ER+/HER2- breast cancer link high IFN signaling to resistance to treatment.

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From The Labs

Not all human norovirus strains are created equal, in their sensitivity to interferon

September 22, 2020 gastroenteritis,  human intestinal enteroids,  human norovirus,  Interferon,  Research

A new study reveals that human norovirus strains differ in sensitivity to the body’s first line of defense.

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From The Labs

Connecting interferon, neuroinflammation and synapse loss in Alzheimer’s disease

March 5, 2020 Alzheimer's Disease,  complement system,  IFN,  Interferon,  microglia,  neuroinflammation,  Research,  synapse loss

When immunologist Dr. Wei Cao joined Baylor College of Medicine three-and-a-half years ago, her first project was to investigate how inflammation contributes to Alzheimer’s disease.

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From The Labs

Surviving bodily defenses: human rotavirus manipulates immune response to maintain infection

January 24, 2017 evasion of immune response,  Gastrointestinal diseases,  human intestinal enteroids,  Interferon,  model of human gut,  rotavirus

The gut of a child infected with rotavirus is like a battleground. On one side, the virus invades the epithelial cells that form the lining

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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