From The Labs Archives - Page 34 of 94 - Baylor College of Medicine Blog Network

Selecting the right deconvolution method just got easier

April 15, 2021 analysis of complex cell populations, deconvolution methods, Research, RNA-seq

Extensive evaluation of existing deconvolution methods produced guidelines that scientists can use to determine the method that optimally fits their needs.

From The Labs

Closer to human – mouse model more accurately reproduces fatty liver disease

April 13, 2021 chimeric mouse model, fatty liver disease, NAFLD, Research

A mouse model that closely replicates fatty liver disease can be used to better understand the condition and identify effective therapies.

From The Labs

Prolonged infection and inflammation drain immune responses as we age

April 8, 2021 Aging, clonal hematopoiesis, Dnmt3a, hematopoietic stem cells, IFNgamma, inflammation, prolonged infection, Research

Sustained infection and inflammation wear down the immune system as we age reducing its ability to fight disease.

From The Labs

Fine-tuning deep brain stimulation plus exercise restore movement in ataxia

April 6, 2021 ataxia, deep brain stimulation, Purkinje cells, Research

A precise combination of DBS and exercise rescued and maintained limb coordination and stepping in mice without further stimulation.

From The Labs

Image of the Month: Training and neuronal activation in Rett mice

April 1, 2021 mental and motor dissability, neuronal arborization, physical training, Research, Rett Syndrome

Early physical training triggers more dendritic arbors or cellular projections in hippocampal neurons (red), enhancing their functionality.

From The Labs

Phages can prevent infection before it happens

March 30, 2021 Antibiotic-resistant bacteria, epithelial cella, ES17 phage, ExPEC bacteria, heparan sulfate, mucins, phages, Research

Researchers have identified a novel strategy that can eliminate bacteria in a specific location before they cause an infection.

From The Labs

Research opens new possibilities to improve the lives of girls with Rett syndrome

March 25, 2021 neuron arborization, physical training, Research, Rett Syndrome

In a mouse model of Rett syndrome, early intensive training substantially delayed the appearance of symptoms and improved performance.

From The Labs

The multitasking nature of SRC-3

March 23, 2021 Breast Cancer, cancer survival, immune system, Research, SRC-3, steroid hormone, T regulatory cells

SRC-3 not only influences steroid hormone function and gives a heads up for aggressive human breast cancer, it also regulates immune T cells.

From The Labs

Identifying rare genetic variants that increase risk for lung cancer

March 18, 2021 ATM, DNA damage, DNA repair, exome sequencing, genomic instability, lung cancer, MLNR, Pomc, Research

Exome sequencing identified new variants that lead to higher levels of DNA damage, which increases the susceptibility for multiple cancers.

From The Labs

Plant integration in the Kendal Hirschi Lab

March 16, 2021 agriculture, Nutrition, plant research, Research

The Kendal Hirschi Lab provides a unique perspective integrating fundamental plant science with basic nutrition research.