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Understanding the cascade of molecular events leading to Rett syndrome
The need for language inclusivity in clinical research
Caring for your feet with a diabetes diagnosis
Mapping functional relations among proteins and genes helps illuminate their role in cancer
Occupational therapy: what patients need to know

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Research

Anticipating treatment response in triple negative breast cancer

September 26, 2024 B cells, Research, response to cancer treatment, triple-negative breast cancer

A new blood biomarker discovered in triple negative breast cancer patients could potentially indicate response to treatment.

Intestinal stem cells have a hard time ‘forgetting’ an encounter with inflammation

September 24, 2024 bone marrow transplant, GVHD, inflammation, intestinal stem cells, Research

Inflammation in the gut leaves long-term marks on intestinal stem cells that affect their response to future challenges.

Medical student-mentor teams in research: Adel Hassan and Dr. Nandan Mondal share their experience with SOAR

September 19, 2024 cardiovascular research, medical students in research, mentor-student teams, Research, SOAR

A medical student and his mentor share how the SOAR program brought them together to conduct basic science research and how the experience is shaping their careers.

P-bodies are part of the survival strategies of acute myeloid leukemia

September 12, 2024 Acute myeloid leukemia, AML, cancer survival, P bodies, Research, tumor suppressor genes

The findings suggest that P-bodies might be an Achilles’ heel of acute myeloid leukemia, opening new avenues for developing anticancer agents to treat this condition.

A healthy spinach salad with chicken and cranberries.

Trying to balance hunger and guilty pleasures? Penk neurons are here to help

September 10, 2024 brain circuits in feeding, DBB-Penk neurons, hunger, Obesity, pleasure eating, Research

Penk neurons in the brain support an ideal, balanced feeding pattern in unexpected ways.

Researchers discovered novel and unique neural signature for depression

September 5, 2024 anhedonia, beta activity in the ACC, Depression, neural signature, Research

This signal could improve diagnosis and monitoring of symptoms of severe depression and other anhedonia-related psychiatric conditions.

Image of the Month: Aging signs

September 3, 2024 Aging, cell nucleus, Hutchinson-Gilford Progeria Syndrome, lamin A, Research

Overexpression of lamin A (red) causes structural changes to the cell nucleus that are associated with aging.

Not just a ‘bad guy,’ Tau also plays a ‘good guy’ role protecting our brains

August 30, 2024 Alzheimer's Disease, glia, lipid droplets, neuronal damage, Research, ROS, tau

This study opens the door to potential new strategies to slow, reverse and treat neurodegenerative conditions.

Alterations in human gene TRPC5 cause obesity and postpartum depression

August 29, 2024 Obesity, postpartum depression, Research, TRPC5

TRPC5 acts on a brain region that regulates multiple innate behaviors including feeding, anxiety, socialization and maternal care.

Gene splicing gone wrong leads to aggressive medulloblastoma

August 27, 2024 alternative splicing, medulloblastoma, OTX2, pediatric brain cancer, PPHLN1, Research

Disturbing OTX2’s gene-splicing ability reduced tumor growth, opening possibilities for improved treatments.

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From the Labs: Image of the Month

From the Labs: Humans are complex genetic mosaics.

Healthy Habits: A DOC-umentary Series

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