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Research

From The Labs 

April is National Autism Awareness Month

April 12, 2022April 12, 2022fruit fly, microbiome, National Autism Awareness Month, PTEN, Research, single-cell connections, Vaccines

From the Labs presents a sample of Baylor’s basic research work contributing to a better understanding of autism and related disorders.

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From The Labs 

Researchers identify two distinct tuberculosis subtypes – one has better prognosis than the other

April 7, 2022April 7, 2022endotypes, precision medicine, Research, TB, TB subtypes, tuberculosis

The study of the human immune response to tuberculosis revealed an approach that can lead to the development of personalized therapies.

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From The Labs 

Video of the Month: A cell dividing

April 5, 2022May 4, 2022cell division, confocal microscopy, mitochondria, Poche lab, Research, science videos

Cell division is a highly dynamic and energy-demanding process.

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From The Labs 

Estrogen-regulated brain circuit helps females control obesity

March 31, 2022March 31, 2022brain circuit, estrogen, Obesity, physical activity, Research, weight control

An estrogen-activated brain circuit connects specific brain regions, providing anti-obesity benefits in an animal model.

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caregiver-alzheimers
From The Labs 

Oleic acid, a key to activating the brain’s ‘fountain of youth’

March 29, 2022March 29, 2022Alzheimer's Disease, Depression, Memory, neurogenesis, oleic acid, Research, TLX

Oleic acid produced in the brain is an essential regulator of the process that enables learning and memory and proper mood regulation.

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From The Labs 

Tuberculosis induces premature cellular aging

March 24, 2022March 24, 2022cellular aging, DNA methylation, epigenetic clock, epigenetics, Research, TB, tuberculosis

It’s possible that premature cellular aging in TB is one reason why survivors have a three-fold increased risk of mortality.

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From The Labs 

Targeting TGF-β for treatment of osteogenesis imperfecta

March 22, 2022March 22, 2022brittle bone disease, fresolimumab, osteogenesis imperfecta, Research, TGF-β, treatment

A monoclonal antibody therapy that neutralizes TGF-β produced promising results in a Phase 1 clinical trial.

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From The Labs 

The fruit fly helps unravel the genetics of autism

March 17, 2022March 17, 2022ASD, Autism, autism genes, fruit fly, GLRA2, Neurodevelopmental diseases, Research

In this study, ASD emerges not as one disorder involving many genes, but as hundreds of disorders caused by certain individual gene variants.

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From The Labs 

Restoring long-term memory recall in a mouse model of Rett syndrome

March 15, 2022March 15, 2022hippocampus, long-term memory recall, OLM cells, Research, Rett Syndrome, SOM neurons

Researchers have discovered that diminished memory recall in Rett syndrome mice can be restored by activating specific inhibitory cells in the hippocampus.

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From The Labs 

SRC-3 is a key regulator of the 12-hour clock

March 10, 2022March 15, 202212-hour biological clock, chronotherapeutics, circadian rhythm, circatidal rhythm, Research, SRC-3, tides, XBP1

Altered 12-hour cycles have been associated with human diseases and hundreds of genes have been identified that are activated in 12-hour cycles.

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From the Labs Image of the Month

From The Labs Image of the Month From the Labs: A closer look at tertiary lymphoid structures. Image courtesy of M. Zelazowski/ P. Castro/Baylor’s Human Tissue Acquisition & Pathology (HTAP) Core.

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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