Research

From The Labs 

Fruit flies: ‘living test tubes’ to rapidly screen potential disease-causing human genes

May 22, 2018May 22, 2018 Ana Rodríguez 0 Comments fruit fly, Model organisms, Research, TBX2, undiagnosed diseases

It all began with one young patient; a 7-year old boy who was born without a thymus, an important organ

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From The Labs 

This is what the Warburg pathway can do for breast cancer growth

May 17, 2018May 18, 2018 Ana Rodríguez 0 Comments Breast Cancer, glucose metabolism, Metastasis, PFKFB4, Research, SRC-3, Warburg pathway

To generate energy from glucose, cells can use one of two pathways. One of them takes place in the mitochondria,

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From The Labs 

Special delivery of IL-7 signaling makes all the difference for CAR T cells fighting solid tumors

May 15, 2018May 15, 2018 Ana Rodríguez 0 Comments brain tumor, CAR T cells, IL7, immunotherapy, Research, solid tumors

Since he was in college, Thomas Shum wanted to pursue a career in cancer research. As he advanced in his

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From The Labs 

The 2018 Michael E. DeBakey M.D. Awards for Excellence in Research

May 10, 2018May 10, 2018 Ana Rodríguez 0 Comments DeBakey Research Awards, Research

Once again, the 2018 DeBakey Research Awards ceremony fulfilled expectations in all attendees. Not only was the event an opportunity

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From The Labs 

USP15 could be a target in ovarian cancer scientists have been looking for

May 8, 2018May 8, 2018 Ana Rodríguez 0 Comments lysosome, ovarian cancer, ovarian steroids, p53, p53-R175H, proteasome, Research, steroid receptor coactivator, USP 15

Ovarian cancer is currently treated with surgery and chemotherapy. Chemotherapy for ovarian cancer is based on drugs that act on

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From The Labs 

Scorpion venom component may one day treat rheumatoid arthritis

May 3, 2018May 3, 2018 Ana Rodríguez 0 Comments fibroblast-like synoviocytes, iberiotoxin, Potassium channels, Research, rheumatoid arthritis, scorpion, scorpion venom

Scorpions inspire fear and fascination. Since ancient times, medical practitioners have known that scorpion venom can heal as well as

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From The Labs 

Image of the Month: SCA1-like neurodegeneration

May 1, 2018May 1, 2018 Ana Rodríguez 0 Comments ataxia, mouse model, Neurodegeneration, pumilio, Purkinje cells, Research, spinocerebellar ataxia type 1

In a mouse model of spinocerebellar ataxia type 1 (SCA1), mice carrying mutant Pumilio1 genes develop progressive motor deficits and cerebellar

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From The Labs 

The Cancer Genome Atlas ten-year study produces game changers for translational research

April 26, 2018April 27, 2018 Ana Rodríguez 1 Comment cancer classification, Cancer Genome Atlas, cancer treatment, Research, TCGA

Historically, cancer patients have been classified according to the organs where primary tumors present at diagnosis, and clinical trials commonly

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From The Labs 

Two is better than one, to improve brain function on a mouse model of Alzheimer’s disease

April 24, 2018April 27, 2018 Ana Rodríguez 0 Comments Alzheimer's Disease, amyloid-beta, mouse model, mTOR, Research

Many of the therapies that are currently being developed to treat Alzheimer’s disease focus on reducing the levels of amyloid-beta,

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From The Labs 

When protein regulators go awry, neurological disease may follow

April 19, 2018April 27, 2018 Ana Rodríguez 0 Comments Alzheimer's Disease, Ataxin1, Mouse models, neurological disease, PUMILIO1, Research, SCA1

Scientists are expanding their horizons in their search for disease-causing genes. Consider for instance a neurological condition called spinocerebellar ataxia

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