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From The Labs

AKAP8 and the delicate balance between normal and metastatic states

March 12, 2020 AKAP8,  alternative splicing,  Breast Cancer,  CD44,  CLSTN1,  metastatis,  Research

A protein naturally produced in the body has been found to suppress breast cancer metastasis in animal models of human tumors. “Our laboratory investigates cellular

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mammogram-photo
The Stitch

Reconstruction procedure gives breast cancer survivor new outlook

February 21, 2020 Breast Cancer,  breast reconstruction,  Dan L Duncan Comprehensive Cancer Center,  Lester and Sue Smith Breast Center,  Michael E. DeBakey Department of Surgery

Ten years ago, when Judy Howell was fundraising for the Lester and Sue Smith Breast Center at Baylor College of Medicine, she had no idea

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From The Labs

Scientists get up close and personal with breast cancer

February 18, 2020 Breast Cancer,  cancer diagnosis,  ErbB2,  HER2,  proteogenomics,  Research

“Patients die from cancer because, at a sufficiently fundamental level, we have not been able to work out what kind of cancer we are treating,”

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From The Labs

Image of the Month: Human breast epithelial cells

February 4, 2020 alternative splicing,  Breast Cancer,  Human breast epithelial cells,  Research

Epithelial cells line the lobules (small lobes) and terminal ducts of the breast and carry out the important function of making milk. Cancer scientists, such

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dna-breast-cancer-final
Momentum

What is the role of genetic counseling in breast cancer care?

October 31, 2019 Breast Cancer,  Cancer,  Dan L Duncan Comprehensive Cancer Center,  Genetic counseling,  Healthcare,  Nicole Blanton

When actress Angelina Jolie revealed that she was a carrier of a genetic mutation that increases her risk of developing breast cancer and ovarian cancer,

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From The Labs

What to expect within the tumor microenvironment

September 17, 2019 Breast Cancer,  breast cancer diversity,  immune cells in tumor,  macrophages,  neutrophils,  Research,  tumor microenvironment

Breast cancer is very heterogeneous. For many years researchers have recognized different subtypes of breast cancer, for instance, estrogen receptor positive (ER+), ER- and triple

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From The Labs

De-escalating breast cancer therapy; can some patients be spared chemotherapy?

June 25, 2019 Breast Cancer,  Chemotherapy,  Clinical Trials,  HER2 gene,  lapatinib,  PI3K pathway,  Research,  trastuzumab

About one of every five breast cancers presents with high levels of HER2 proteins. Known as HER2-positive breast cancer, these tumors typically show an aggressive

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From The Labs

CD44 variants prompt different cancer cell behaviors

February 21, 2019 alternative splicing,  Breast Cancer,  cancer heterogeneity,  cancer plasticity,  CD44,  Metastasis,  Research,  resistance to treatment

Imagine fighting enemies that differ in their susceptibility to the weapon you are using against them. Some will perish, but others will survive the attack

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From The Labs

A potential Achilles’ heel of breast cancer bone metastasis

December 6, 2018 Achilles' heel,  bone metastasis,  bone-in-culture,  Breast Cancer,  calcium,  mTOR,  Research

Researchers have found that the bone microenvironment can promote the growth and progression of breast cancer micrometastasis, a small group of cancer cells that separates

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miller-bonefas-photo
Momentum

Above and beyond: Breast cancer treatment for the whole person

November 1, 2018 Allison Mickey,  Breast Cancer,  Cancer,  Courtney Vastine,  Dan L Duncan Comprehensive Cancer Center,  Dr. Matthew Ellis,  Healthcare,  triple-negative breast cancer

Stephanie D. Miller knew breast cancer ran in her family, and with her dense breast tissue, she was religious about getting her annual mammogram. She

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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