Elevated cryptic transcription emerges as a common theme in aging mammalian cells
Evidence suggests that reducing the amount of this aberrant transcription in aging organisms might help prolong lifespan.
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Aging
Prolonged infection and inflammation drain immune responses as we age
Sustained infection and inflammation wear down the immune system as we age reducing its ability to fight disease.
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Image of the Month: The laboratory worm, C. elegans
What is transparent, as long as a credit card is thick and helps solve science mysteries? The laboratory worm, C. elegans.
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Light-activated genes illuminate the role of gut microbes in longevity
Optogenetics, a method that uses light to regulate gene expression, can control gut bacterial metabolism to promote longevity.
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Glutathione precursor GlyNAC reverses premature aging in people with HIV
Twenty years of research support the role of antioxidant glutathione in reversing premature aging in people with HIV.
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Early postnatal overnutrition sets the body on a fast track to aging
Overnutrition during early infancy can have adverse health consequences later in life. Although researchers have known this for quite some time, the explanations have been
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Extending the body’s expiration date may involve the ends of the chromosomes
Scientists may have found a strategy to achieve the science-fictional greeting “Live long and prosper.” In his lab at Baylor College of Medicine, Dr. Ergun
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A worm’s lessons for living a longer, healthier life
Caenorhabditis elegans is a seemingly unimpressive worm. It is as long as a penny is thick, it lives in the soil feeding on microbes it
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Alternative splicing is crucial to muscle mass maintenance
Despite the importance that changes in muscle mass have in aging, overall body metabolism and in chronic disease, we still don’t fully understand the mechanisms
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Image of the Month: Lipid droplets in the transparent worm C. elegans
Meet Caenorhabditis elegans, a 1-millimeter-long, transparent, free-living roundworm that is the center of attention of many research laboratories around the world, including Dr. Meng Wang‘s
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