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From The Labs

Supertwists and loops provide a new perspective on how DNA may regulate its function

October 19, 2021 DNA function regulation, Research, supercoiling and looping DNA

DNA’s shape may regulate accessibility in situations such as response to drugs, infection or points in the cell cycle.

PBRM1’s new function supports a novel cancer-promoting mechanism

October 14, 2021 Cancer, chromatin remodeler, cytoskleleton remodeler, genomic instability, kidney cancer, PBRM1, Research, SETD2, tubulin methylation

New findings suggest that cancer-associated defects in chromatin remodeler genes can drive cancer by disrupting cytoskeletal activities.

It’s all in the delivery – Antibodies improve nanoparticle delivery of therapeutic nucleic acids

October 13, 2021 antibody targeted nanoparticles, LGA-PEI polymer delivery system, pancreatic cancer, Research, therapeutic nucleic acids

This improved technological platform can be used to develop new treatments, molecular diagnosis strategies or vaccines for various diseases.

Loss of gene Prss50 results in abnormal sperm tail development and infertility

October 12, 2021 abnormal sperm tail, fertility diagnostic tools, male infertility, PRSS50, Research, sperm, untimely gene expression

Lacking Prss50 disrupts the timely activation of certain genes, and this leads to abnormal sperm development.

Baylor College of Medicine celebrates research excellence with DeBakey Awards

October 7, 2021 Allzhemier's, Autism, brain coding, brain function, COVID vaccine, DeBakey Research Awards, Diabetes, glia, liver disease, Research

The 2021 DeBakey Research Awards go to: Dr. Benjamin Deneen, Dr. Hana El Sahly, Dr. Fasiha Kanwal, Dr. Nuo Li and Dr. Zheng Sun.

Image of the Month: First place, 2021 Nikon Small World Photo Competition

October 5, 2021 first place Nikon photo contest, Microscopy, plant life, Research, stomata, trichomes

Three essential elements of plant life raised to the top of Nikon’s Small World Photomicrography Competition.

KLF4 displays novel mechanism for influencing gene expression

September 30, 2021 biomolecular condensate, DNA, gene expression, KLF4, methylation, Research, zinc fingers

KLF4 can cause DNA to condense into a separate liquid phase that recruits other factors that contribute to gene expression.

Studying gene function is now easier, faster and more efficient

September 28, 2021 drug-based selection and counterselection, fruit fly, gene function, genetic studies, Research

A drug-based genetic platform enables scientists to follow genetic manipulations in the laboratory fruit fly more efficiently.

Hallucinogen drug LSD helps understand how the brain generates behavior

September 23, 2021 brain alterations, brain map, hippocampus, LSD, research behavior, visual cortex

LSD triggers changes in the brain that may explain the profound altered behavior associated with the drug in animal models.

National Postdoc Appreciation Week 2021

September 21, 2021 National Postdoc Appreciation Week, Research

From the Labs celebrates National Postdoc Appreciation Week with a sample of the work conducted by Baylor postdocs.

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Healthy Habits: A DOC-umentary Series

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