Baylor Science Quiz 2022

Have you been keeping up with science discoveries at Baylor College of Medicine?

Test your knowledge by answering these 20 questions:

1. Name the Baylor faculty member who was elected to the AAAs board of directors in 2022.
2. What normal bone process has been linked to the initiation of bone metastasis?
3. Name three factors that act synergistically increasing the risk for liver disease.
4. What is the strategy Baylor Tailor Labs uses to combat antibiotic-resistant bacterial infections?
5. Name a faster, brighter and more sensitive sensor for brain electrical activity developed at BCM.
6. What supplement has shown to improve a wide variety of age-associated deficiencies in older adults in a clinical trial?
7. Name four of the eight BCM faculty members who received the Michael E. DeBakey M.D. Award for Excellence in Research in 2022.
8. What is the most common birth defect of the central nervous system and the second most common of all structural birth defects?
9. Name the molecule in the blood that is produced during exercise and can effectively reduce food intake and obesity in mice.
10. What cell organelle produces signals that cells use to coordinate longevity across different tissues?
11. Name the innovative, faster and more cost-effective drug discovery tool developed at Baylor’s Center for Drug Discovery that enables researchers to screen billions of compounds all in one test tube.
12. What approach led researchers to identify a new high-risk subtype of pediatric liver cancer?
13. What cellular organelle did Baylor researchers discover to contribute to the degradation of dying cells, in addition to and in parallel of lysosomes?
14. What IFN-mediated process is rather harmful to synapses, affecting memory and cognitive performance?
15. Name the common fatty acid that increases cell proliferation and neurogenesis in the hippocampus of both young and old mice.
16. What infectious disease was associated with premature aging?
17. What condition has been associated with increased levels of a protein called transforming growth factor-β (TGF-β) in bones and connective tissues of mouse models and patients?
18. What laboratory tool has enabled researchers to closely study the early events of RSV and COVID-19 infection in the nose?
19. What strategy can revert large scar tissue into working muscle and potentially be a part of therapy for heart failure?
20. Where do tertiary lymphoid structures typically develop?

ANSWERS:

1. Susan Rosenberg https://blogs.bcm.edu/2022/05/17/from-the-labs-dr-susan-rosenberg-elected-to-aaas-board-of-directors/
2. The bone repair process. https://blogs.bcm.edu/2022/11/16/from-the-labs-dissemination-of-bone-metastasis-linked-with-bone-remodeling/
3. Obesity, alcohol use, genetic variant PNPLA3. https://blogs.bcm.edu/2022/10/11/from-the-labs-genetic-and-behavioral-risks-combine-synergistically-for-liver-disease/
4. They use phages to combat bacteria. https://blogs.bcm.edu/2022/09/08/from-the-labs-tailor-achieves-clinical-success-combating-antibiotic-resistant-microbes-with-phage-therapy/
5. JEDI-2P https://blogs.bcm.edu/2022/08/30/from-the-labs-meet-jedi-2p-a-faster-brighter-and-more-sensitive-sensor-for-brain-electrical-activity/
6. GLyNAC . https://blogs.bcm.edu/2022/08/23/from-the-labs-glynac-reverses-aging-hallmarks-in-older-adults/
7. https://blogs.bcm.edu/2022/08/18/from-the-labs-baylor-college-of-medicine-recognizes-research-excellence-with-debakey-awards-2/
8. Spina bifida. https://blogs.bcm.edu/2022/08/04/from-the-labs-raising-awareness-of-spina-bifida/
9. Lac-Phe. https://blogs.bcm.edu/2022/06/16/from-the-labs-the-benefits-of-exercise-in-a-pill-science-is-closer-to-that-goal/
10. Lysosomes. https://blogs.bcm.edu/2022/06/14/from-the-labs-talking-about-aging-lysosomes-have-something-to-say/
11. DNA-Encoded Chemistry Technology (DEC-Tec). https://blogs.bcm.edu/2022/06/07/from-the-labs-a-faster-less-expensive-approach-identifies-highly-specific-anti-cancer-compounds/
12. Molecular profiling of tumors, including genetic alterations and gene expression profiles. https://blogs.bcm.edu/2022/05/24/from-the-labs-molecular-profiling-identifies-new-high-risk-subtype-of-pediatric-liver-cancer/
13. Autophagosomes https://blogs.bcm.edu/2022/05/10/from-the-labs-new-insights-into-the-fate-of-dying-cells/
14. Interferon-mediated inflammatory pathway. https://blogs.bcm.edu/2022/04/19/from-the-labs-interferon-drives-cognitive-impairment-in-alzheimers-disease-model/
15. Oleic acid. https://blogs.bcm.edu/2022/03/29/from-the-labs-oleic-acid-a-key-to-activating-the-brains-fountain-of-youth/
16. Tuberculosis.https://blogs.bcm.edu/2022/03/24/from-the-labs-tuberculosis-induces-premature-cellular-aging/
17. Osteogenesis imperfecta. https://blogs.bcm.edu/2022/03/22/from-the-labs-targeting-tgf-%ce%b2-for-treatment-of-osteogenesis-imperfect/
18. Nose organoids. https://blogs.bcm.edu/2022/02/22/from-the-labs-miniature-model-of-the-human-nose-reveals-early-events-of-sars-cov-2-and-rsv-infection/
19. Cell reprograming https://blogs.bcm.edu/2022/01/06/from-the-labs-innovative-approach-brings-cell-reprogramming-therapy-for-heart-failure-closer-to-reality/
20. In non-immune tissues at sites of chronic inflammation, including tumors https://blogs.bcm.edu/2022/05/06/from-the-labs-image-of-the-month-a-closer-look-at-tertiary-lymphoid-structures/

By Ana María Rodríguez, Ph.D.