From The Labs Archives - Page 19 of 99 - Baylor College of Medicine Blog Network

Eliminating gene SRC-3 in immune cells triggers effective long-lasting anti-cancer response

June 8, 2023 Breast Cancer, cancer treatment, Prostate Cancer, Research, SRC-3, Tregs, tumor microenvironment

The findings in animal models warrant continuing investigations to develop a novel, more effective and longer-lasting cancer therapy.

From The Labs

Major primate genome sequencing studies reveal new insight into evolution, biodiversity and key applications for human health

June 6, 2023 biodiversity, Evolution, human health, primate genome, Research

These studies improve our understanding of both human biology and practical clinical issues.

A person seen from behind who is holding their back as if in pain.

From The Labs

Gene Tiam1 orchestrates the development of chronic neuropathic pain

May 31, 2023 antisense oligonucleotides, Chronic Pain, gene Tiam1, neuropathic pain, Research, spinal cord

The findings open new possibilities for novel therapies to provide much needed relief to patients with this condition.

From The Labs

Changes in gene p16 create a permissive microenvironment for colon cancer growth

May 25, 2023 APC gene, Colorectal Cancer, DNA methylation, epimutation, p16, polyps, Research, tumor microenvironment

The researchers also developed a strategy that reduced tumor growth and improved survival in tumor-bearing mice.

From The Labs

Breast cancer tumors remotely disrupt immune response that could stop their own growth

May 23, 2023 anti-tumor response, bone marrow microenvironment, Breast Cancer, MMP-13, remote immunosuppression, Research

The researchers identified ways to accelerate the restoration of the normal immune response and the efficacy of immunotherapies in animal models.

From The Labs

19th Annual Texas Children’s Cancer and Hematology Center Research Symposium

May 18, 2023 Cancer and hematology research symposium, medulloblastoma, Research, sickle cell anemia

Researchers discussed the latest cutting-edge, translational and clinical research focusing on pediatric hematology and oncology.

From The Labs

Discovering targetable vulnerabilities in endocrine therapy-resistant breast cancer

May 16, 2023 endocrine therapy-resistant breast cancer, ER+ breast cancer, estrogen receptor 1, fusion genes, pralsetinib, Research, RET kinase

The findings support evaluating targeting kinase enzymes in a clinical trial to treat this type of breast cancer.

From The Labs

GlyNAC supplementation improves cognitive decline and brain health in aging

May 11, 2023 Aging, brain health, cognitive decline, glutathione deficiency, GlyNAC, Research

GlyNAC – a combination of precursors of the natural antioxidant glutathione – improved or reversed age-associated cognitive decline in old mice and improved multiple associated defects in the aging brain.

From The Labs

Variants of MRTFB gene linked to novel neurodevelopmental disorder

May 9, 2023 actin-binding protein, fruit fly, MRTFB gene, neurodevelopmental disorder, Research, undiagnosed disease

The findings open new avenues to investigate mechanisms that lead to this disorder, offering ideas toward a future treatment for the disease.

From The Labs

Neurons lead the way in the development of astrocytes

May 4, 2023 astrocyte development, GABA B receptor, neurons, Research

Neurons trigger a complex pattern of events, some of them unexpected, that direct astrocyte development in a region-specific manner.