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From The Labs

From The Labs 

Image of the Month: Hues of HeLa

February 1, 2021February 1, 2021 Ana Rodríguez 0 Comments GI infection, HeLa, Image competition, Image of the month, Research

Our own Dr. Kristen Engevik is the winner of “CELL-ebrating HeLa” image competition with the image “Hues of HeLa.”

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From The Labs 

Light-activated genes illuminate the role of gut microbes in longevity

January 28, 2021January 28, 2021 Ana Rodríguez 0 Comments Aging, C. elegans, colanic acid, Longevity, microbiome, optogenetics, Research

Optogenetics, a method that uses light to regulate gene expression, can control gut bacterial metabolism to promote longevity.

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From The Labs 

Engineering meets biology to design innovative multifunctional surgical Biomesh

January 27, 2021January 27, 2021 Ana Rodríguez 0 Comments 3D printed surgical Biomesh, hernia repair, inflammation, Research, X-PVA

An innovative, 3D printed surgical Biomesh not only provides mechanical support but also plays a physiological role of reducing the inflammatory response that causes significant clinical problems.

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From The Labs 

Connecting the dots between lactating mother’s diet, milk composition, microbiome and benefits of mother’s milk

January 26, 2021January 26, 2021 Ana Rodríguez 0 Comments Breastfeeding, diet, HMO, metabolic health, milk microbiome, Research

This study reports the first evidence that the mother’s diet while breastfeeding can shape the profile of HMOs, a type of food for microbes, which in turn modifies the functional abilities of the milk microbiome.

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From The Labs 

Waking up sleeping beauty – persistent IFN-gamma awakens and activates stem cells via BST2

January 21, 2021January 21, 2021 Ana Rodríguez 0 Comments blood stem cells, bone marrow transplant, BST2, E-selectin, homing, IFN, Infectious diseases, Research

The researchers show that persistent IFNγ mediates the exhaustion of blood stem cells via BST2 expression.

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From The Labs 

Study of spliceosome-targeting cancer therapies reveals an overlooked role of mis-spliced RNAs themselves

January 19, 2021January 19, 2021 Ana Rodríguez 0 Comments apoptosis, cancer treatment, Immunotherapy, Research, RNA splicing, Spliceosome-targeting therapies, triple-negative breast cancer

Endogenous mis-spliced RNA in tumor cells mimics an RNA virus, leading tumor cells to self-destruct as if fighting an infection.

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From The Labs 

BICRA gene variants linked to a neurodevelopmental disorder

January 14, 2021January 14, 2021 Ana Rodríguez 0 Comments BICRA gene, Coffin-Siris syndrome, fruit fly, neurodevelopmental disease, neurodevelopmental disorder, Research, zebra fish

Genetic testing of an undiagnosed condition triggered a study that linked the BICRA to a neurodevelopmental disorder.

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From The Labs 

‘Rule-breakers’ help identify novel gene variants that modify risk of late-onset Alzheimer’s disease

January 12, 2021January 14, 2021 Ana Rodríguez 0 Comments ADSP, APOE, fruit fly, genetic risk, Late-onset Alzheimer’s disease, Research

Using novel methodologies, researchers identified 216 new gene variants, many previously not suspected to play a role in Alzheimer’s disease.

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From The Labs 

Rhesus macaque genome study enhances our understanding of human genetic variation

January 7, 2021January 14, 2021 Ana Rodríguez 0 Comments genetic variation, reference genome, Research, Rhesus macaque

Substantially improved rhesus macaque genome reference assembly helps answer fundamental questions in genetics, cell biology and physiology.

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From The Labs 

The Most Viewed Image of the Month in 2020

January 5, 2021January 5, 2021 Ana Rodríguez 0 Comments AKOX1, Image ofthe month, research myelin, Schwann cells, sciatic nerve

‘Transverse view of the sciatic nerve’ placed on top as the most viewed Image of the Month in 2020.

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From the Labs Image of the Month

From The Labs Image of the Month From the Labs features an image of the laboratory worm, Caenorhabditis elegans. Image credit: Dr. Tao Chen/Wang lab.

Healthy Habits: A DOC-umentary Series

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