Research Archives - Page 72 of 90 - Baylor College of Medicine Blog Network

In his lab at Baylor College of Medicine, Dr. Hugo Bellen and his colleagues work with the fruit fly, Drosophila melanogaster, as a model system

From The Labs

Preventing sudden cardiac death with genome editing

October 30, 2018 cardiomyocytes, catecholaminergic polymorphic ventricular tachycardia, CRISPR/Cas9, inherited cardiac arrhythmia disorders, R176Q, Research, RyR2, sudden cardiac death

Each year, at least 3 million people worldwide die of sudden cardiac death. In the U.S., this number reaches up to 450,000 people. Although sudden

From The Labs

Estrogen receptor can affect resistance to endocrine therapy and metastasis in breast cancer

October 25, 2018 Breast Cancer, ESR1, estrogen receptor-positive, Metastasis, Research, resistance to endocrine therapy

Resistance to therapy is common in estrogen receptor positive (ER+) breast cancer, the most common type of breast cancer, and eventual development of metastatic disease

From The Labs

INSiGHT into neural fate in the retina

October 23, 2018 INSiGHT, neural development, Research, retina, retinal regulators, Slc44a1, vasculature in the retina

Vision begins in the retina, a light-sensing neural network in the eye that is critical for our ability observe the world around us. “Unless we

From The Labs

UPDATE: The dark side of antibiotic ciprofloxacin

October 18, 2018 antibiotic, aortic aneurysms and dissections, ciprofloxacin, fluoroquinolones, PRAC, product warning, Research, vascular endothelium

In July 2018, From the Labs released a post on the laboratory evidence suggesting that in a mouse model of moderately stressed aortas, exposure to

Momentum

Understanding the importance of metastatic breast cancer research

October 17, 2018 Allison Mickey, Breast Cancer, Lester and Sue Smith Breast Center, Metastatic breast cancer, Research

Dr. Suzanne Fuqua shares what inspired her to get involved in metastatic breast cancer research and how she is educating the public about scientific advances at Baylor College of Medicine and beyond.

From The Labs

Mom and dad genes and the intricate process of gene regulation

October 16, 2018 DNA methylation, epigenome, gene regulation, genome, Research, SD-ASM, WGBS

If the genome is like computer hardware, then the epigenome is the software that turns certain genes on and others off. During development, the epigenome

From The Labs

McNair Scholar Spotlight: Dr. Xiang “Shawn” Zhang

October 11, 2018 bone metastasis, Breast Cancer, McNair scholar, Research

From the Labs sat down with McNair Scholar Dr. Xiang “Shawn” Zhang to learn more about him, his research, his motivations to pursue a career

From The Labs

Turning unexpected results into research tools

October 9, 2018 chloride ion channel, GtACR2, light-gated channel, neuron, optogenetic tools, Research

One way to study neuronal function is by altering the activity of the neurons and then observing the outcomes, just like in genetics where scientists

From The Labs

Predicting gain-of-function mutations linked to disease

October 4, 2018 analytical tool, gain of function mutation, genetic disease, loss of function mutation, Mendelian genomics, Research, Robinow syndrome

Genes can cause disease because of mutations that result in loss-of-function; for instance, when the mutated gene is not producing the protein it encodes. But