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RyR2

From The Labs

Novel mechanism connects SPEG, RyR2 and atrial fibrillation

August 13, 2020August 13, 2020atrial fibrillation, heart disease, Research, RyR2, SPEG

Reduced levels of protein kinase SPEG lead to hyperactive calcium channel RyR2 and an increased risk of atrial fibrillation.

From The Labs

Preventing sudden cardiac death with genome editing

October 30, 2018October 30, 2018cardiomyocytes, catecholaminergic polymorphic ventricular tachycardia, CRISPR/Cas9, inherited cardiac arrhythmia disorders, R176Q, Research, RyR2, sudden cardiac death

Each year, at least 3 million people worldwide die of sudden cardiac death. In the U.S., this number reaches up to 450,000 people. Although sudden

From The Labs

'Leaky calcium' gene linked to sudden cardiac death in epilepsy

October 10, 2016epilepsy, leaky calcium gene, Neuroscience, RyR2, spreading depolarization, sudden cardiac death

[See video below] Epilepsy is an extremely common disorder affecting people of all ages, from infants through teenagers to older adults. One of the most

From the Labs: a transparent heart