Research Archives - Page 25 of 79 - Baylor College of Medicine Blog Network

Oleic acid, a key to activating the brain’s ‘fountain of youth’

March 29, 2022 Alzheimer's Disease, Depression, Memory, neurogenesis, oleic acid, Research, TLX

Oleic acid produced in the brain is an essential regulator of the process that enables learning and memory and proper mood regulation.

From The Labs

Tuberculosis induces premature cellular aging

March 24, 2022 cellular aging, DNA methylation, epigenetic clock, epigenetics, Research, TB, tuberculosis

It’s possible that premature cellular aging in TB is one reason why survivors have a three-fold increased risk of mortality.

From The Labs

Targeting TGF-β for treatment of osteogenesis imperfecta

March 22, 2022 brittle bone disease, fresolimumab, osteogenesis imperfecta, Research, TGF-β, treatment

A monoclonal antibody therapy that neutralizes TGF-β produced promising results in a Phase 1 clinical trial.

From The Labs

The fruit fly helps unravel the genetics of autism

March 17, 2022 ASD, Autism, autism genes, fruit fly, GLRA2, Neurodevelopmental diseases, Research

In this study, ASD emerges not as one disorder involving many genes, but as hundreds of disorders caused by certain individual gene variants.

From The Labs

Restoring long-term memory recall in a mouse model of Rett syndrome

March 15, 2022 hippocampus, long-term memory recall, OLM cells, Research, Rett Syndrome, SOM neurons

Researchers have discovered that diminished memory recall in Rett syndrome mice can be restored by activating specific inhibitory cells in the hippocampus.

From The Labs

SRC-3 is a key regulator of the 12-hour clock

March 10, 2022 12-hour biological clock, chronotherapeutics, circadian rhythm, circatidal rhythm, Research, SRC-3, tides, XBP1

Altered 12-hour cycles have been associated with human diseases and hundreds of genes have been identified that are activated in 12-hour cycles.

From The Labs

GlyNAC supplementation extends life span in mice

March 8, 2022 Aging, glutathione, GlyNAC, hallmarks of aging, mitochondrial deficiency, mouse model, oxidative stress, Research

GlyNAC – a combination of precursors of the natural antioxidant glutathione – can increase lifespan and improve multiple key age-associated defects in mice.