How MAGE-A4 helps tumors evade immune responses crucial for their elimination
The next step could include human clinical trials to test potential therapeutic avenues to restore the ability to fight the tumor.
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Research
Rare chromosome reshuffling leads to severe complex form of epilepsy
Although it’s more commonly found in cancer, chromosome reshuffling is increasingly identified in neurodevelopmental disorders.
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Uncovering unique features of early onset colorectal cancer in racial and ethnic minorities
The findings bring hope and direction to better understand this emerging condition and support continuing these studies.
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Hear this – researchers are mapping the cells that tune in to sound
The findings challenge long-standing principles of hearing processing in the brain and offer fresh avenues for therapeutic exploration.
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Rotavirus protein NSP4 manipulates gastrointestinal disease severity
The findings suggest that regulating NSP4 could lead to new strategies to prevent or treat rotavirus infections.
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Sprinter and marathoner CAR T cells reveal their distinct cancer-killing behavior
The study lays a foundation for designing CAR molecules that maximize antitumor activity beyond B cell malignancies.
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Discovering replication hubs of human norovirus
The findings offer potential new targets for antivirals to treat this serious threat to children and immunocompromised patients.
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From bench to bedside and back: CAR T cells armed with IL-15 show promise in treating solid cancers
Researchers relate their journey to finding a promising method to address CAR T cell challenges in treating solid tumors.
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Feeling hungry? Beginning a meal starts in the brain
This study reveals brain circuits and chemical messengers that contribute to the regulation of meal initiation and food intake.
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Top five most viewed Images of the Month in 2024
Our viewers selected these Images of the Month as the most popular of 2024.
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