Scientists uncover nuclear droplets that link multiple leukemias, a potential new therapeutic target
The study reveals that different genetic drivers of leukemia use the same compartments inside the cell nucleus to keep cancer growing.
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Research
Research suggests that Alzheimer’s disease may develop through distinct biological pathways
This study analyzes fruit fly and human data to offer new insights into how Alzheimer’s disease risk genes affect the brain.
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Researchers make strides toward preventing parenteral nutrition-associated liver disease
This research paves the way for new clinical interventions that could dramatically improve outcomes in this vulnerable pediatric population.
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Brain “stars” hold the power to preserve cognitive function in model of Alzheimer’s disease
The findings suggest a potential astrocyte-based therapeutic approach to ameliorate cognitive decline in neurodegenerative disease.
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Human ‘mini-noses’ help understand why RSV infections are more severe in children than in adults
The findings represent a step toward a more effective personalized RSV care by providing the first detailed cell atlas of RSV infection of the human nose and revealing age-related differences that influence which cells RSV infects and how the body responds.
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Baylor College of Medicine resident co-authors groundbreaking cancer paper in Nature
From the Labs sat with Dr. Rishabh Lohray, a first-year dermatology resident, to learn about his experiences as a member of the research team and a little about him.
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Image of the Month: Human intestinal organoid
Human intestinal organoids, also called ‘mini-guts,’ provide a laboratory model to study human intestinal epithelial biology and the processes leading to intestinal disease.
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How GREGoR Consortium is advancing the diagnostics of rare diseases
Learn about the major accomplishments of the consortium’s first five years and the frontiers in genomic medicine that researchers will tackle next.
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In Memoriam: Bert W. O’Malley, M.D.
During his decades-long career, Dr. Bert O’Malley changed our understanding of endocrinology in a fundamental way.
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p53 mutant R273H opens new avenues for future personalized cancer treatment
This study highlights the importance of understanding the specific type of p53 mutation in each patient’s tumor, as it may influence both disease behavior and therapeutic strategies.
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