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kidney cancer

From The Labs

PBRM1’s new function supports a novel cancer-promoting mechanism

October 14, 2021October 14, 2021 Ana Rodríguez 0 Comments Cancer, chromatin remodeler, cytoskleleton remodeler, genomic instability, kidney cancer, PBRM1, Research, SETD2, tubulin methylation

New findings suggest that cancer-associated defects in chromatin remodeler genes can drive cancer by disrupting cytoskeletal activities.

From The Labs

Playing with the physics of gels leads to a better kidney cancer treatment

May 14, 2020May 21, 2020 Ana Rodríguez 0 Comments cancer treatment, FDA approved, Jelmyto, kidney cancer, mitomycin, Research, UGN-101, Urothelial cancer

Effectively treating upper tract urothelial cancer – a cancer of the lining of the kidney or the ureter, the long, thin tube that connects that

From The Labs

Chromosome remodeler SETD2 also remodels the cytoskeleton in kidney cancer cells

August 30, 2016March 9, 2018 Ana Rodríguez 0 Comments Cancer, chromosome remodeler, cytoskeleton remodeler, epigenetics, kidney cancer, methyl tags, Research, SETD2

Kidney cancer begins when certain genes mutate and, as a result, alter how key molecules work. One of these key molecules is SETD2, which is

From the Labs features a visualization of a novel approach to study gene function in the fruit fly. Image courtesy of the study authors/Cell Reports, 2021.