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SETD2

From The Labs 

PBRM1’s new function supports a novel cancer-promoting mechanism

October 14, 2021October 14, 2021 Ana Rodríguez 0 Comments Cancer, chromatin remodeler, cytoskleleton remodeler, genomic instability, kidney cancer, PBRM1, Research, SETD2, tubulin methylation

New findings suggest that cancer-associated defects in chromatin remodeler genes can drive cancer by disrupting cytoskeletal activities.

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From The Labs 

Changing the perspective on the ‘Cinderella of the cytoskeleton’

December 23, 2020December 23, 2020 Ana Rodríguez 0 Comments actin, Cancer, cytoskeleton, filaments, HTT, methylation, microtubules, Research, SETD2, WHAMM

Actin modifications, such as those described here, are increasingly being recognized as key regulators of cytoskeleton dynamics.

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From The Labs 

Chromosome remodeler SETD2 also remodels the cytoskeleton in kidney cancer cells

August 30, 2016March 9, 2018 Ana Rodríguez 0 Comments Cancer, chromosome remodeler, cytoskeleton remodeler, epigenetics, kidney cancer, methyl tags, Research, SETD2

Kidney cancer begins when certain genes mutate and, as a result, alter how key molecules work. One of these key molecules is SETD2, which is

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From the Labs Image of the Month

From The Labs Image of the Month From the Labs Confocal microscopy image showing the striatum in a mouse model of Huntington’s disease. Image courtesy of Dr. Juan Botas/eLife, 2021.

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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