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From The Labs

Rearranging genomic structure rewires gene control in cancer

November 14, 2019 Cancer,  cancer genetics,  Cancer Genome Atlas,  DNA methylation,  epigenetics,  genomic structural variation,  immune infiltration,  Research

Widespread DNA damage is common in the cancer genome. Understanding the mechanisms that lead to it is of great interest to cancer physicians and scientists

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From The Labs

Getting to know TP53 better

August 15, 2019 Cancer,  Cancer Genome Atlas,  chromosomal deletion,  gene duplication,  Research,  TP53

TP53 is well known for its role as a tumor suppressor. It senses cellular stress or damage and in response stops cell division or initiates

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From The Labs

What altered gene regulatory regions can do for cancer

September 20, 2018 Cancer,  Cancer Genome Atlas,  gene regulation,  genomic structural rearrangements,  Research

The genome includes genes – sequences of DNA that encode the proteins that keep our body working – and regulatory regions adjacent to genes, which

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From The Labs

The Cancer Genome Atlas ten-year study produces game changers for translational research

April 26, 2018 cancer classification,  Cancer Genome Atlas,  cancer treatment,  Research,  TCGA

Historically, cancer patients have been classified according to the organs where primary tumors present at diagnosis, and clinical trials commonly test drugs that are designed

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From The Labs

Common altered pathways provide new cancer perspective

March 29, 2018 Cancer,  cancer classification,  Cancer Genome Atlas,  immune checkpoint,  metabolic pathways,  neuroendocrine tumor,  Research

Studying cancer at the molecular level has revealed that there is not a single pathway or process that drives all the different types of cancer.

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From The Labs

Opening a window into the world of tumors

February 8, 2017 Breast Cancer,  cancer cells,  Cancer Genome Atlas,  computational analysis,  epigenome,  International Human Epigenome Consortium,  transcriptome

A tumor behaves like a community in which cancerous and normal cells interact with each other. In some cases, these interactions result in tumor growth,

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From The Labs

How understanding tumor diversity can potentially improve the outcomes of patients with lung cancer

November 28, 2016 Cancer,  Cancer Genome Atlas,  cancer molecular profile,  Genetics,  Immunotherapy,  immunue check point,  lung cancer,  lymphocyte infiltration

[See video below] “People may think of lung cancer as one disease, but lung cancer is a collection of diverse subtypes of cells and each

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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