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From The Labs

Immune checkpoint therapy for ER+ breast cancers, a missed opportunity?

December 5, 2019 endocrine treatment resistant breast cancer,  ER+ breast cancer,  immune check points,  luminal A breast cancer,  luminal B breast cancer,  Research

In the United States, apart from some forms of skin cancer, breast cancer is the most common cancer in women. It is also the most

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From The Labs

Top six most viewed Images of the Month, 2019

December 3, 2019 Image of the month,  Research

From the Labs wraps up the Image of the Month feature for the year by presenting a slide show with the top six most viewed

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From The Labs

Applying basic science helps predict poor treatment outcomes in ALL

November 21, 2019 Acute Lymphoblastic Leukemia,  ALL,  carbon metabolism,  metabolome,  Pediatric Cancer,  prognosis,  Research

The survival of patients with pediatric acute lymphoblastic leukemia (ALL) has significantly improved in the last several decades, but there is still a group of

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From The Labs

Unraveling how PTEN deficiency can lead to autism

November 19, 2019 antisense oligonucleotide,  Autism,  autism spectrum disorders,  mTOR,  PTEN,  Research

Autism is a developmental disorder that affects 1 in 59 children in the U.S. Mutations in specific genes, such as PTEN, can explain many autism

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From The Labs

Rearranging genomic structure rewires gene control in cancer

November 14, 2019 Cancer,  cancer genetics,  Cancer Genome Atlas,  DNA methylation,  epigenetics,  genomic structural variation,  immune infiltration,  Research

Widespread DNA damage is common in the cancer genome. Understanding the mechanisms that lead to it is of great interest to cancer physicians and scientists

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From The Labs

‘Give me the calcium!’ Tulane virus takes over cellular calcium signaling to replicate

November 12, 2019 gastrointestinal virus,  human norovirus,  NS1-2,  Research,  rotavirus,  Tulane virus,  viroporin

Some gastrointestinal viruses need calcium. They need calcium ions to carry out several essential aspects of viral life, such as entry into host cells, genome

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From The Labs

Learning to stop cancer at its roots

November 7, 2019 chronic myeloid leukemia,  CML,  DYRK2,  Research,  stem cell renewal,  stem cells,  tyrosine kinase inhibitors.,  vitamin K3

Why do some cancers come back? Sometimes, a treatment can effectively eliminate cancer cells to undetectable levels, but, if the treatment stops, cancer may return.

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Cardiofibroblasts Martin FTL
From The Labs

Image of the Month: cardiac fibroblasts

November 5, 2019 cardiac fibroblasts,  heart attack,  heart failure,  Hippo pathway,  LATS 1/2,  Research

This Image of the Month features the cardiac fibroblast, a cell that is central to heart failure, the leading cause of mortality in the U.S.

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From The Labs

Molecular profiling of meningioma hints at tumor behavior

October 31, 2019 DREAM,  meningioma,  molecular profiling,  Research,  WHO

Meningiomas, the most common primary brain tumors, are typically benign. One-fifth of them, however, recur despite complete surgical removal. Reliably predicting whether a patient’s tumor

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From The Labs

Congratulations Dr. Peggy Goodell, Baylor’s new member of the National Academy of Medicine!

October 29, 2019 NAM,  National Academy of Medicine;,  Research

  Dr. Margaret “Peggy” Goodell, chair of the Department of Molecular and Cellular Biology at Baylor College of Medicine, has been elected to the National Academy of Medicine.

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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