The first protease-focused, DNA-encoded chemical library for drug discovery
Scientists at Baylor College of Medicine have devised a chemical approach for discovering compounds that could be developed into new drugs.
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Novel mechanism connects SPEG, RyR2 and atrial fibrillation
Reduced levels of protein kinase SPEG lead to hyperactive calcium channel RyR2 and an increased risk of atrial fibrillation.
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CAR T cell therapy makes strides in tackling Hodgkin lymphoma
CAR-T cell therapy has been used to treat Hodgkin lymphoma with remarkable success for the first time in an early phase clinical trial.
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Tackling the root cause of treatment resistance in age-related macular degeneration
A novel strategy can potentially address a major challenge to the current treatment for CNV, the leading cause of irreversible blindness in the elderly.
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Image of the Month: Cancer cell clusters
Cancer cell clusters are more effective than single cells at spreading cancer in the body, and researchers at Baylor College of Medicine found out why.
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The N-terminal domain of the androgen receptor is at the heart of its action
Detailed 3-D studies reveal how the androgen receptor is put together as a functional complex that drives prostate cancer.
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Taking a closer look into the tumor microenvironment with nano-radiomics
Nano-radiomics analysis of imaging data assesses changes in the tumor microenvironment that cannot be detected with conventional imaging methods.
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PolyA-miner accurately assesses the effect of alternative polyadenylation on gene expression
PolyA-miner enables scientists to evaluate the contribution of alternative polyadenylation to gene regulation in health and disease.
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New insights into the mediators of patient recovery after CAR T cell immunotherapy
Clinical trial of novel personalized CAR T cell immunotherapy provides clues into what mediated exceptional patient recovery.
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These 300,000 cells can improve our understanding of chronic lung disease
Researchers create a digital atlas for chronic lung disease.
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