Ana Rodríguez, Author at Baylor College of Medicine Blog Network

A promising two-punch therapy for Langerhans cell histiocytosis

June 29, 2021 dendritic cells, Langerhans cell histiocytosis, MAPK inhibitor, PD-1 receptors, rare cancer, Research, T-cell exhaustion

A novel combination therapy resulted in a significant decrease of disease burden in an animal model of LCH.

From The Labs

Book release: “Genomics of Rare Diseases. Understanding Disease Genetics Using Genomic Approaches”

June 25, 2021 book release, Genetics, Genomics, Rare Diseases, Research

“Genomics of Rare Diseases” offers readers a broad understanding of current knowledge on rare diseases from a genomics perspective.

From The Labs

Glial cells help mitigate neurological damage in Huntington’s disease

June 24, 2021 brain protection, fruit fly model, glia cells, Huntington’s disease, mouse model, Research, synapse genes

Research with human samples and mouse and fruit fly models opens a window into the brain’s protective responses in Huntington’s disease.

From The Labs

Rap1 controls the body’s sugar levels from the brain, regulating it may help manage diabetes

June 22, 2021 Brain, Diabetes, high-fat diet, hypothalamus, Rap1, Research, VMH neurons

One day, people might be able to control diabetes from the brain.

From The Labs

Repairing altered novel brain circuit could tackle coinciding obesity and depression

June 17, 2021 Anxiety, brain circuit, dBNST and AgRP neurons, Depression, Obesity, Research

Study reveals key regulatory mechanism for coinciding obesity and mental disorders and suggests the possibility of pharmacological treatment.

From The Labs

Gene Rev-erb in the brain sets the rhythm of the liver’s response to insulin

June 15, 2021 Brain, Diabetes, GABA neurons, liver, Research, Rev-erb gene, suprachiasmatic nucleus

The findings support that an altered daily rhythm of expression of the Rev-erb gene in the brain may underlie dawn phenomenon in diabetes.

From The Labs

Image of the Month: Bovine endothelial cells dividing

June 9, 2021 Bovine endothelial cells, confocal microscopy, OiVM Core, Research

The image is an example of the cutting-edge imaging and image analysis tools offered by Baylor’s Optical Imaging & Vital Microscopy Core.

From The Labs

NANOS2 and failed sperm development linked to testicular cancer

May 20, 2021 NANOG, NANOS2, Research, sperm development, testicular cancer

NANOS2-deficient germ cells failed to mature into sperm, remained pluripotent and were more likely to transform into embryonic cancer cells.

From The Labs

The bone microenvironment ‘empowers’ cancer cells to become metastatic

May 18, 2021 bone microenvironment, Breast Cancer, EZH2, Metastasis, Prostate Cancer, Research

The bone microenvironment prompts changes in breast cancer cells that help them escape treatment and become more invasive.

From The Labs

The Cardiovascular Research Institute 8th Annual Symposium

May 14, 2021 aortic aneurysms, atherosclerosis, atrial fibrillation, COVID, CVRI, heart disease, Research, symposium

Review the symposium highlights, visit the virtual poster session and meet the winners of the first Dr. Mark L. Entman Award for Excellence in Cardiovascular Education.