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dendritic cells

From The Labs

A promising two-punch therapy for Langerhans cell histiocytosis

June 29, 2021June 29, 2021dendritic cells, Langerhans cell histiocytosis, MAPK inhibitor, PD-1 receptors, rare cancer, Research, T-cell exhaustion

A novel combination therapy resulted in a significant decrease of disease burden in an animal model of LCH.

From The Labs

A novel mechanism that triggers a cellular immune response

June 11, 2020June 11, 2020Cancer, cell-mediated immune response, dendritic cells, MHC Class I, MHC Class II, Research, Vaccines, viral infection

Viruses and other disease-causing microbes influence the type of immune response their hosts will develop against them. In some cases, the predominant response involves antibodies,

From The Labs

Discovery of CTLA-4 in dendritic cells opens new possibilities to fight cancer

April 15, 2016Cancer, cancer immunity, CTLA-4, dendritic cells, Immunology, ipilimumab, tumor vaccine

By Ana María Rodríguez, Ph.D. In the battle against cancer, T cells are the ‘foot soldiers’ and dendritic cells are ‘the generals.’ Cancer cells are

From the Labs: A closer look at tertiary lymphoid structures. Image courtesy of M. Zelazowski/ P. Castro/Baylor’s Human Tissue Acquisition & Pathology (HTAP) Core.