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From The Labs

Researchers identify an Achilles’ heel in neuroblastoma

August 16, 2022 cancer treatment,  FATP2,  fatty acid metabolism,  metabolimics,  MYCN,  neuroblastoma,  Research

A metabolic vulnerability in neuroblastoma could be exploited to overturn these tumors’ resistance to therapy.

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From The Labs

Throwback Thursday: The first Image of the Month

August 11, 2022 DNA-dependent protein kinase,  estrogen receptor alpha,  Image of the month,  Research,  science cartoon,  Throwback Thursday

For years after the first one was posted, we have continued to feature amazing research images from Baylor labs every month.

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Lung cancer, illustrated here as round masses inside the lungs, the second most common cancer in both men and women.
From The Labs

Genome-wide study reveals new susceptibility genetic variants for lung cancer

August 9, 2022 genome-wide study,  lung cancer,  Research,  risk factors

This study revealed five new susceptibility genes, 10 new variant associations from known risk genes and further validated in different populations another 24 associations.

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From The Labs

Raising awareness of spina bifida

August 4, 2022 Birth defects,  folic acid,  neural tube defects,  Research,  spina bifida

From the Labs sat with Dr. Richard H. Finnell to learn more about spina bifida.

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From The Labs

Video of the Month: A beating developing mouse heart

August 2, 2022 beating heart,  cardiogenesis,  high-resolution imaging,  optical coherence tomography,  Research

Innovative live high-resolution imaging and dynamic analysis enable the study of the mammalian heart at early developmental stages.

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From The Labs

Changing the perspective on the origin of enzymatic catalytic power

July 28, 2022 artificial enzyme design,  destabilization of ground states,  enzymatic catalysis,  noncovalent interactions,  Research,  stabilization of transition states,  water

The findings have important implications not only to better understand the catalytic power of enzymes but also for practical drug design applications.

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From The Labs

Researchers discover novel light-gated potassium channel

July 26, 2022 channelrhodopsins,  light-gated ion channels,  optogenetics,  potassium channel,  Research

A new class of light-gated channels promises to pave the way for rapid and efficient optical neuronal silencing.

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From The Labs

Unanticipated findings cast new light on the genetic regulation of different brain tumors

July 21, 2022 brain tumor,  ependymoma,  epigenetics,  EPN,  gene regulation,  HGG,  high-grade glioma,  Research,  SOX9,  tumor behavior

The findings highlight the importance of considering the mechanisms of gene regulation involved in different tumors when planning therapies.

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From The Labs

Brain sphingolipid metabolism is closely involved in Gaucher disease

July 19, 2022 Gaucher disease,  glia,  glucosylceramide,  lipid metabolism,  lysosomes,  neurodegenerative disease,  neurons,  Parkinson's Disease,  Research,  sphingolipid

Disruption of sphingolipid metabolism led to neurodegeneration in animal models, revealing a new molecular path to Gaucher’s disease.

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From The Labs

Emu has improved the accuracy of bacterial identification

July 7, 2022 16S,  bacterial identification,  microbiome,  next-generation sequencing,  Research,  rRNA

Emu can advance our understanding of the roles of the microbiome in water, soil and the intestinal tract.

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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