Missing “copy” of Jag1 gene results in mouse model for Alagille syndrome
By Julia Parsons When mice usually used in studies of genetic disease lack a copy of the jagged gene (Jag1), they have many of the
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From The Labs
Normal levels of "Goldilocks" protein in mouse model restores neurologic function in MECP2 duplication syndrome
By Ruth SoRelle, M.P.H. For 15 years and more, Dr. Huda Zoghbi, professor of molecular and human genetics at Baylor College of Medicine, and director of
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Image of the Month: Mouse breast tumor cells
Mouse mammary carcinoma 4T1 cells in pseudo-colored scanning electron micrographs. These mouse breast tumor cells (shown in these pseudo-colored scanning electron micrograph, are used to
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The writhing and coiling of DNA drives cell activity
By Ruth SoRelle, M.P.H. Using a multidisciplinary approach, researchers, led by those at Baylor College of Medicine, revealed in unprecedented detail the three-dimensional structure of
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Image of the Month: Organizing DNA
A multi-institutional team spanning Baylor College of Medicine, Rice University, Stanford University, and the Broad Institute of MIT and Harvard has reported the first successful
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CRISPR/Cas9 : Disruptive or Innovative?
Stirring high-profile debates over the past few months, the controversial genome editing technique, CRISPR/Cas9, continues to make scientific headlines. The June 4, 2015 issue of
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Deep brain stimulation overcomes cognitive deficits in Rett mice
Deep brain stimulation — usually used to treat movement disorders – overcomes the learning and memory deficits in mice whose symptoms mimic those of Rett
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Image of the Month — Carbon black nanoparticles at fault in emphysema
By Ruth SoRelle, M.P.H. Autopsies on smokers who died with severe emphysema reveal lungs that are black in appearance. These emphysematous lungs strain breathing structures
Read MoreA matter of health: How 2015 Nobel Prize drug might rid Africa of ancient scourges
By Dr. Peter Hotez The announcement that the 2015 Nobel Prize in Physiology or Medicine went to three scientists who developed antiparasitic disease drugs has
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Novel epigenetic signature for tumor suppressors in normal cells found
By Glenna Vickers An epigenetic feature that may help identify novel cancer driver genes has been identified by researchers in the Dan L. Duncan Cancer
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