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A model valentine-style heart sitting next to a stethoscope.
From The Labs

Gasdermin D emerges as a potential therapeutic target for atrial fibrillation

March 27, 2025 atria,  atrial fibrillation,  Dementia,  gasdermin D,  heart cells,  heart failure,  mitochondria,  reactive oxygen species,  Research,  Stroke

This study reveals that gasdermin D plays a novel role in the development of atrial fibrillation through multifaceted mechanisms.

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A pregnant person's torso seen from the side, their arms wrapped around their stomach. A lush green wooded area is seen behind them.
From The Labs

Postpartum female preference for cooler temperatures linked to brain changes

March 25, 2025 body temperature,  ERαPOA neurons,  female temperature preference,  lactation,  mouse brain,  Postpartum,  Pregnancy,  Research

Changes in temperature preference in postpartum female mice were associated with significant alterations in the preoptic area of the brain.

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From The Labs

Medical student-mentor teams in research: Anna Norman and mentor Dr. Nancy Moran share their experience with SOAR

March 20, 2025 basic research training,  carotenoids,  genetics of skin carotenoids,  medical students,  research mentor,  SOAR

Meet Anna Norman and her mentor Dr. Nancy Moran as they have a conversation about how the SOAR program brought them together to conduct basic science research and how the experience is shaping their careers.

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A doctor listening to a patient's heart
From The Labs

Restoring heart function in Myotonic Dystrophy Type 1

March 18, 2025 DM1,  DM1 therapies,  heart problems,  Myotonic Dystrophy Type 1,  Research

The findings are relevant to current therapeutic approaches for DM1 that are based on increasing MBNL protein.

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From The Labs

Of mice and people: study reshapes our understanding of ageing and disease

March 13, 2025 Aging,  blood stem cells,  mouse,  people,  Research

This work gives us a more complete understanding of the factors that influence how a tissue ages over an organism’s lifetime.

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From The Labs

AI accelerates the discovery of genes associated with neurodevelopmental disorders

March 11, 2025 AI modeling,  Autism Spectrum Disorder,  developmental delay,  epilepsy,  Genes,  neurodevelopmental disorders,  Research

The researchers hope that their models will also lead to patient diagnoses, and future studies will assess this possibility.

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From The Labs

Breakthrough cardiac regeneration research offers hope for the treatment of ischemic heart failure

March 6, 2025 calcium,  Cardiac regeneration,  heart failure,  LTCC,  Research

The premise of regenerating heart tissue, which once seemed like an impossible dream, is getting closer almost daily.

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From The Labs

Image of the Month: Zika virus builds underground tunnels

March 4, 2025 human placenta,  Research,  stealth transmission,  tunneling,  Zika virus

This is the first time that tunneling has been shown by Zika virus infection in placental cells.

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patient-friend-photo
From The Labs

Long-term survival supports the potential benefit of CAR T cell therapy to treat solid tumors

February 27, 2025 CAR T cell therapy,  Clinical Trials,  disease free,  longest survival,  neuroblastoma,  Research,  solid tumors

An 18-year survivor of neuroblastoma is believed to represent the longest reported remission to date in a patient treated with chimeric antigen receptor (CAR) T cell therapy.

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A graphic illustration of a family that appear as silhouettes filled with germs.
From The Labs

Understanding the world within: study reveals new insights into phage–bacteria interactions in the gut microbiome

February 25, 2025 bacteria,  diabetes type 1,  microbiome,  phages,  Research,  TEDDY study

By evaluating temporal trends in the guts of developing children, this study helps to lay the groundwork for therapeutics and diagnostics leveraging the microbiome and its constituents.

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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