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Vaping and mental health: What’s the connection?
In a cell-eat-cell world calcium ions regulate exposure of ‘eat-me’ signal in necrotic cells
Progress Notes MS1/MS4 profile: Ashley Cooney
Image of the Month: Brain of a mouse model of Huntington’s Disease
Fasting lowers blood pressure by reshaping the gut microbiota

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RNA splicing

From The Labs

Study of spliceosome-targeting cancer therapies reveals an overlooked role of mis-spliced RNAs themselves

January 19, 2021January 19, 2021 Ana Rodríguez 0 Comments apoptosis, cancer treatment, Immunotherapy, Research, RNA splicing, Spliceosome-targeting therapies, triple-negative breast cancer

Endogenous mis-spliced RNA in tumor cells mimics an RNA virus, leading tumor cells to self-destruct as if fighting an infection.

From The Labs

Image of the Month: What causes myotonic dystrophy, type1

September 5, 2017 Ana Rodríguez 0 Comments alternative splicing, CELF1 and MBNL proteins, CTG repeat, CUGexp, DM1, DMPK gene, MEF2 transcription factor, muscular dystrophy, myotonic dystrophy, RNA splicing

Myotonic dystrophy, type 1 (DM1) is the second most common cause of muscular dystrophy and numerous other muscle disorders that affect tens of thousands of

From the Labs features an image showing the striatum in the brain of a mouse model of Huntington’s Disease. Image courtesy of Dr. Juan Botas/eLife, 2021.