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Image of the Month: The laboratory worm, C. elegans

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RNA splicing

From The Labs

Study of spliceosome-targeting cancer therapies reveals an overlooked role of mis-spliced RNAs themselves

January 19, 2021January 19, 2021 Ana Rodríguez 0 Comments apoptosis, cancer treatment, Immunotherapy, Research, RNA splicing, Spliceosome-targeting therapies, triple-negative breast cancer

Endogenous mis-spliced RNA in tumor cells mimics an RNA virus, leading tumor cells to self-destruct as if fighting an infection.

From The Labs

Image of the Month: What causes myotonic dystrophy, type1

September 5, 2017 Ana Rodríguez 0 Comments alternative splicing, CELF1 and MBNL proteins, CTG repeat, CUGexp, DM1, DMPK gene, MEF2 transcription factor, muscular dystrophy, myotonic dystrophy, RNA splicing

Myotonic dystrophy, type 1 (DM1) is the second most common cause of muscular dystrophy and numerous other muscle disorders that affect tens of thousands of

From the Labs features an image of the laboratory worm, Caenorhabditis elegans. Image credit: Dr. Tao Chen/Wang lab.