triple-negative breast cancer Archives - Baylor College of Medicine Blog Network

These finding highlight new possibilities for developing clinical interventions to treat metastatic TNBC patients for whom there are no specific therapies.

From The Labs

New cell markers to track the most aggressive breast cancer in blood

January 29, 2026 cancer detection, circulating tumor cells, liquid biopsy, metastatic cancer, patent, Research, triple-negative breast cancer

Tumor cells that were frequently undetectable using standard markers became clearly visible when the team applied the new marker combination.

From The Labs

Fatty acids promote immune suppression and therapy resistance in triple negative breast cancer

April 22, 2025 immune suppression, lipids, neutrophils, Omega-6 fatty acids, Research, triple-negative breast cancer, tumor microenvironment

The researchers show that disrupting lipid formulation reverses treatment resistance and the immunosuppressive microenvironment.

From The Labs

DAPK3 emerges as a new regulator of migration of triple-negative breast cancer cells

October 8, 2024 cancer cell migration, DAPK3, desmoplakin, LUZP1, Research, triple-negative breast cancer

The researchers’ next steps include studying how DAPK3 promotes TNBC migration and assess its potential value as a therapeutic target.

From The Labs

Anticipating treatment response in triple negative breast cancer

September 26, 2024 B cells, Research, response to cancer treatment, triple-negative breast cancer

A new blood biomarker discovered in triple negative breast cancer patients could potentially indicate response to treatment.

From The Labs

eIF4A emerges as a potential Achilles’ heel for triple-negative breast cancer

October 31, 2023 cancer vulnerability, eIF4A, Research, triple-negative breast cancer, Zotatifin

Targeting eIF4A to interfere with the synthesis of proteins the cancer needs to grow is producing promising results.

Two slides showing breast cancer cells as blue or green dots on a blue background.

From The Labs

A potential strategy to control MAPK4-dependent cancer growth

August 8, 2023 AKT, cancer growth, lung cancer, MAPK4, PDK1, Prostate Cancer, Research, triple-negative breast cancer

This study has advanced our understanding of the molecular mechanisms underlying the tumor-promoting activity of MAPK4.

From The Labs

Serendipity reveals an opportunity to improve the success of chemotherapy in triple negative breast cancer

July 27, 2023 kinase inhibitor, KIPA, purine-binding protein, Research, TNBC, triple-negative breast cancer

Researchers identified a tumor protein signature that predicts chemotherapy sensitivity and favorable clinical outcomes.

From The Labs

Research reveals markers of chemotherapy resistance and outcome in triple negative breast cancer

September 6, 2022 chemotherapy resistance, microscaled proteogenomics, Research, triple-negative breast cancer

The findings help predict tumor response so that only effective treatments are given.

From The Labs

Combating triple-negative breast cancer on two fronts delivers promising results

April 28, 2022 combination therapy, CSF1R, macrophages, Research, triple-negative breast cancer

Researchers identified a combination therapy for triple-negative breast cancer that results in durable tumor regression in an animal model.

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