Research Archives - Page 10 of 79 - Baylor College of Medicine Blog Network

5D4 disrupts several molecular pathways, including MYC, that lead to cancer growth

October 26, 2023 5D4, Breast Cancer, cancer inhibitor, MYC, ovarian cancer, PARP inhibitor, Research, TopBP1

The findings strongly support the potential use of TopBP1 inhibitors as a targeted cancer therapy.

A graphic illustration of a family that appear as silhouettes filled with germs.

Can changing the gut microbiome alter the course of a disease?

October 24, 2023 bone marrow transplant, butyrate, clinical trial, dietary intervention, graft-versus-host disease, gut microbiome, potato starch, Research

A simple, safe dietary intervention has an effect on the gut microbiome and metabolites in these patients.

From The Labs

Deep brain stimulation induces more healthy neurons and sustained memory benefits in Rett animal models

October 19, 2023 brain-derived neurotrophic factor, deep brain stimulation, MECP2, Research, Rett Syndrome

DBS results in a significant and long-lasting improvement to memory in Rett animal models strongly suggesting evaluating this approach to treat Rett patients.

From The Labs

Fungal infection in the brain produces changes like those seen in Alzheimer’s disease

October 17, 2023 Alzheimer's Disease, amyloid precursor protein, Brain, C. albicans, cnadidalysin, fungus, Parkinson's Disease, Research, Saps

This work potentially contributes an important new piece of the puzzle regarding the development of Alzheimer’s disease.

From The Labs

Path-breaking research reveals new possibilities to improve treatment of endometrial carcinoma

October 12, 2023 cancer treatment, endometrial cancer, gynecologic cancers, PIK3R1-AKT pathway, proteogenomic characterization, Research

Detailed molecular characterization of endometrial carcinomas identifies potential markers for guiding more precise treatment.

From The Labs

Highlighting breast cancer research at Baylor College of Medicine

October 10, 2023 Breast Cancer Awareness Month, Research

From the Labs joins Breast Cancer Awareness Month highlighting recent breast cancer research at Baylor College of Medicine.

From The Labs

d16 reduces tumor growth and overcomes therapeutic resistance in mutant p53-bearing cancers

October 5, 2023 Cancer, d16, Dna2, Research, therapeutic resistance, tumor growth

The researchers combined computational and experimental approaches that led to the discovery of d16 and its potential anti-cancer activity.

From The Labs

Image of the Month: Newborn mouse eye

October 3, 2023 blood vessels, Image of the month, macrophages, Research, retina

Microscopic details of a newborn mouse eye showing blood vessels (pink) and macrophage immune cells (green).

From The Labs

PARMESAN: An AI-based predictive tool to find new treatments for genetic disorders

September 28, 2023 AI, genetic disorders, PARMESAN, predictive computational tool, Research

PARMESAN scans public biomedical literature databases, identifies and ranks gene-gene and drug-gene regulatory relationships and even leverages curated information to predict undiscovered relationships.

Transmission electron microscope image of negative-stained, Fortaleza-strain Zika virus.

From The Labs

Researchers combat Zika-associated fetal abnormalities using microRNA

September 26, 2023 animal model, human placenta, immune microenvironment, microRNA, Research, Zika virus

This study reveals new insights into how the Zika virus sets up a niche in the placenta at the maternal-fetal interface.