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From The Labs

Connecting Tau aggregates, transposable elements and neurodegeneration in Alzheimer’s disease

August 2, 2018 Alzheimer's Disease,  genomic instability,  neurlogic diseases,  Neurodegeneration,  Research,  tau,  transposable elements

Although it’s been known for years that the accumulation of Tau protein within brain cells in combination with progressive cell death is one of the

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From The Labs

Image of the Month: SCA1-like neurodegeneration

May 1, 2018 ataxia,  mouse model,  Neurodegeneration,  pumilio,  Purkinje cells,  Research,  spinocerebellar ataxia type 1

In a mouse model of spinocerebellar ataxia type 1 (SCA1), mice carrying mutant Pumilio1 genes develop progressive motor deficits and cerebellar degeneration. Studies conducted by the

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From The Labs

How disrupting mitochondria genes can lead to neurodegeneration

February 20, 2018 idh3a,  mitochondria,  Neurodegeneration,  neurological disease,  neurotransmission,  synapses

Years back, the Bellen lab identified many mutations in genes of the mitochondria, the energy generators of the cell. Among them was a mutation in

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From The Labs

Breakdown of neuron-glia partnership can pave the way to neurodegeneration

November 30, 2017 Alzheimer's Disease,  APOE4,  free radicals,  glia cells,  lipid accumulation,  Neurodegeneration,  neuron

In 2015, Dr. Lucy Liu, now a Ph.D. graduate in neuroscience from the Bellen lab, discovered that a number of genes involved in neurodegeneration promote

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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