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From The Labs

A potential new therapeutic target for Group 3 medulloblastoma

August 8, 2024 CAR T cell,  grade3-medulloblastoma,  Immunotherapy,  pediatric brain cancer,  protogenin,  Research

Researchers identified and located a population of stem-like cells that initiates and maintains Group 3 medulloblastoma in the developing brain.

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From The Labs

Study of spliceosome-targeting cancer therapies reveals an overlooked role of mis-spliced RNAs themselves

January 19, 2021 apoptosis,  cancer treatment,  Immunotherapy,  Research,  RNA splicing,  Spliceosome-targeting therapies,  triple-negative breast cancer

Endogenous mis-spliced RNA in tumor cells mimics an RNA virus, leading tumor cells to self-destruct as if fighting an infection.

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From The Labs

CAR NKT cells, a promising step forward in the treatment of solid tumors

November 10, 2020 CAR NK T cells,  clinical trial,  Immunotherapy,  neuroblastoma,  Research,  solid tumors

An ongoing clinical trial shows that human CAR NKT cells are safe and, in 1 of 3 patients, induced regression of metastatic lesions.

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From The Labs

New insights into the mediators of patient recovery after CAR T cell immunotherapy

July 21, 2020 cancer therapy,  CAR T cell,  Clinical Trials,  complete response,  HER-2,  Immunotherapy,  Research,  rhabdomyosarcoma

Clinical trial of novel personalized CAR T cell immunotherapy provides clues into what mediated exceptional patient recovery.

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Samir-Tanios-CRI
Momentum

Immunotherapy improves quality of life for mesothelioma patient

November 19, 2019 Cancer,  Dan L Duncan Comprehensive Cancer Center,  Healthcare,  Immunotherapy,  Mesothelioma,  Molly Chiu

When Samir Tanios was diagnosed with malignant pleural mesothelioma in September 2018, he was in poor condition. He couldn’t take a deep breath  or walk

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Momentum

Body of Work podcast: Harnessing the body’s immune system to fight cancer

September 16, 2019 Body of Work,  Cancer,  Immunotherapy

By 2030, the number of new cancer cases per year is expected to increase by 23.6 million worldwide. While radiation and chemotherapy continue to be

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From The Labs

Immunotherapy for pancreatic cancer shows promise

July 23, 2019 Conference,  Immunotherapy,  pancreatic cancer,  Research,  T cell therapy

Pancreatic cancer is one of the most challenging types of cancer to treat, but new therapy using the body’s own immune system is providing new

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melanoma-nci-photo-featured
Momentum

How immunotherapy is improving outlook for melanoma patients

June 4, 2019 Cancer,  Dan L Duncan Comprehensive Cancer Center,  Healthcare,  Immunotherapy,  melanoma,  Nicole Blanton,  Skin Cancer

Melanoma is the deadliest form of skin cancer in the world. While traditional therapies include chemotherapy, radiation, and surgery, immunotherapy has emerged as an effective

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From The Labs

From the labs to bedside: First-in-human trial shows promise in treating neuroblastoma

May 28, 2019 chimeric antigen,  Clinical Trials,  GD2,  GD2-CAR,  Immunotherapy,  neuroblastoma,  Research

Neuroblastoma is the most common extracranial solid cancer in children, and patients with high-risk disease are challenging to treat. In April, during the annual meeting of

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From The Labs

Special delivery of IL-7 signaling makes all the difference for CAR T cells fighting solid tumors

May 15, 2018 brain tumor,  CAR T cells,  IL7,  Immunotherapy,  Research,  solid tumors

Since he was in college, Thomas Shum wanted to pursue a career in cancer research. As he advanced in his studies, he was able to

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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