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From The Labs

Machine learning meets biology to assess risk of schizophrenia in a blood sample

August 17, 2021 CoRSIVs,  early diagnosis,  epigenetics,  machine learning,  Psychiatry,  Research,  schizophrenia

A novel machine learning approach can identify schizophrenia patients with 80% accuracy.

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From The Labs

Sorting out cell type-specific molecular barcodes

July 14, 2020 CluBCpG,  DNA methylation,  epigenetics,  PReLIM,  Research,  WGBS

Researchers at Baylor College of Medicine developed novel software that can distinguish methylation patterns within bulk WGBS data.

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From The Labs

A closer look at severe malnutrition

February 11, 2020 DNA methylation,  epigenetics,  ESAM,  malnutrition,  NESAM,  Research

More than two million children die worldwide each year of severe malnutrition. Severe acute childhood malnutrition presents in two clinically distinct forms: edematous severe acute

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From The Labs

The making of a ‘couch potato mouse’

December 30, 2019 AgRP neurons,  couch potato,  DNA methylation,  epigenetics,  Exercise,  hypothalamus,  overnutrition,  Research

Some people love to exercise, but others hate it. Many researchers consider genetics to be the reason for a person’s inclination to exercise, or not

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From The Labs

Rearranging genomic structure rewires gene control in cancer

November 14, 2019 Cancer,  cancer genetics,  Cancer Genome Atlas,  DNA methylation,  epigenetics,  genomic structural variation,  immune infiltration,  Research

Widespread DNA damage is common in the cancer genome. Understanding the mechanisms that lead to it is of great interest to cancer physicians and scientists

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From The Labs

Image of the Month: Islet of Langerhans

October 1, 2019 Diabetes,  DNA methylation,  epigenetics,  insulin,  Islet of Langerhans,  overnutrition,  Research

Cells of the Islets of Langerhans in the pancreas help regulate blood sugar. Disrupting their normal function can contribute to the development of diabetes. The

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From The Labs

This map facilitates the search for epigenetic causes of disease

June 6, 2019 CoRSIV,  DNA methylation,  epigenetics,  genome,  Homa Shalchi,  Research

More than 15 years after scientists first mapped the human genome, most diseases still cannot be predicted based on one’s genes. Thus, researchers also are

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From The Labs

Identical twins share more than identical genes

March 13, 2018 cancer risk,  epigenetics,  identical twins,  Research,  supersimilarity

For decades, researchers have studied genetically identical twins to estimate what proportion of disease risk is determined by one’s genes. This approach should be reevaluated,

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From The Labs

Autism spectrum disorder: if not vaccines, then what?

February 24, 2017 ASD,  Asperger Syndrome,  Autism Spectrum Disorder,  brain growth,  epigenetics,  Global Burden of Disease Study,  vaccines and autism

New information gained from major scientific papers over the last two years has shed light on the causes and progression of autism spectrum disorder.  Estimates

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From The Labs

Chromosome remodeler SETD2 also remodels the cytoskeleton in kidney cancer cells

August 30, 2016 Cancer,  chromosome remodeler,  cytoskeleton remodeler,  epigenetics,  kidney cancer,  methyl tags,  Research,  SETD2

Kidney cancer begins when certain genes mutate and, as a result, alter how key molecules work. One of these key molecules is SETD2, which is

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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