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From The Labs

Image of the Month: Neurogenesis in the adult mouse brain

February 5, 2019 adult brain,  neurogenesis,  Research

  In most adult mammals, only two regions of the brain, the hippocampus and the olfactory bulb, have been shown to integrate new neurons into

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From The Labs

Beyond the airway and into the brain, yeast impairs memory in mice

January 31, 2019 airway disease,  Allergies,  Alzheimer's Disease,  C. albicans,  Dementia,  FIGG,  fungal infection,  fungus,  sepsis,  yeast

An increasing number of clinical observations indicates that fungi are becoming a more common cause of upper airway allergic diseases such as asthma, as well

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From The Labs

E. coli shows the way to discover cell-made protein carcinogens

January 29, 2019 bacteria,  Cancer,  carcinogens,  DNA damage,  E. Coli,  Research

When searching for carcinogens, people look at the environment. External factors such as tobacco smoke and sunlight can damage DNA, triggering mutations that can cause

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From The Labs

Solving the mystery of CLN8’s connection with Batten disease

January 24, 2019 Batten disease,  CLN8,  Lysosomal storage disorder,  neuronal ceroid lipofuscinosis 8,  Research

Batten disease refers to a group of diseases that are part of the lysosomal storage disorders. At the core of these conditions are problems with

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From The Labs

Making ‘sense’ of the ‘cart before the horse’ in mammalian cells

January 22, 2019 antisense RNA,  Cancer,  fusion DNA,  fusion RNA,  Prostate Cancer,  Research,  sense RNA

A fusion gene is a new gene made by joining parts of two different genes. The current thought is that fusion genes can happen in

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From The Labs

Connecting Zika virus and hereditary microcephaly

January 17, 2019 ANKLE2,  dengue virus,  microcephaly,  NS4A,  Research,  Zika virus

Understanding how Zika virus causes microcephaly would hint at possibilities for preventing this irreparable condition in newborns. Heading in that direction, a collaboration between Baylor

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From The Labs

When DNA is caught at the break

January 15, 2019 Cancer,  DNA fragments,  DNA repair,  Dna2,  immune system,  Research

Cells have in place a number of mechanisms to protect the integrity of the genome, including processes that repair mistakes that may occur during DNA

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From The Labs

Putting mind and heart together opens a window into the adult brain

January 10, 2019 adult brain,  cardiovascular research,  olfactory bulb,  Research,  single cell RNA sequencing

The mammalian brain is a complex tissue composed of diverse cell types. However, despite rapid advances in the field of neuroscience, only a limited number

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From The Labs

Mutant PPM1D gives stem cells a survival advantage

January 8, 2019 Cancer,  Chemotherapy,  clonal hematopoiesis,  PPM1D,  Research,  secondary leukemia

Scroll down to watch the video summary of this work. Although chemotherapy can fight back cancer, it also has been associated with increased risk of

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From The Labs

Image of the Month: Assembling a rotavirus factory

January 3, 2019 CK1 alpha,  NSP2,  phsophorylation,  Research,  rotavirus,  rotavirus factory

Making new viruses requires assembling intracellular replication factories via a complex, little known process that involves both viral and cellular components. New insights into this

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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