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From The Labs

Interferon linked to ER+/HER- metastatic breast cancer resistance to therapy

March 12, 2021 CDK4/6 inhibitor therapy,  endocrine therapy,  ER+/HER2- breast cancer,  Interferon,  Metastatic breast cancer,  Research,  resistance to cancr treatment

Both preclinical models and tumor samples from patients with ER+/HER2- breast cancer link high IFN signaling to resistance to treatment.

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From The Labs

International Women’s Day: Interview with Dr. Meagan Pitcher

March 8, 2021 career options,  International Women's Day,  licensing,  Research

Dr. Meagan Pitcher shared her transition from biomedical research to licensing, the nuances of her work and how she keeps in shape.

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From The Labs

Proteomics analysis identifies potential drug targets for aggressive human cancers

March 4, 2021 agrressive cancer,  cancer proteomics,  cancer therapy,  cancer transcriptomics,  Research

Researchers identified proteomic signatures associated with clinical measures of aggressive disease for each of the seven cancer types studied.

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From The Labs

Image of the Month: The laboratory worm, C. elegans

March 2, 2021 Aging,  bacteria,  C. elegans,  Image of the month,  lipid signaling,  mitochondria,  Research

What is transparent, as long as a credit card is thick and helps solve science mysteries? The laboratory worm, C. elegans.

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From The Labs

Black History Month Spotlight: Interview with Dr. Debra Murray

February 28, 2021 biocuration,  Black History Month,  minorities in genomics,  Research,  summer programs

Dr. Debra Murray shared her professional journey, from conducting basic science research to developing and managing programs to interest minority students in genomics.

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From The Labs

Black History Month Spotlight: Interview with Dr. Darius Dawson

February 25, 2021 Black History Month,  educational outreach,  Health Disparities,  mentorship,  Research,  tobacco cessation

Dr. Darius Dawson shared his dedication to improving the health of minority populations, a hint to his artistic side and much more.

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From The Labs

Black History Month Spotlight: Interview with Dr. Kathryn Jones

February 24, 2021 Black History Month,  Chagas disease,  heart disease,  Research,  Vaccines

Dr. Kathryn Jones shared how she discovered her vocation, how she unwinds at the end of the day and much more.

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From The Labs

Targeting MAPK4 emerges as a promising therapy for prostate cancer

February 23, 2021 Akt pathway,  androgen receptor,  cancer therapy,  castration-resistant prostate cancer,  MAPK4,  Prostate Cancer,  Research

Inhibiting MAPK4 simultaneously inactivated both androgen receptor and AKT and stopped cancer growth in animal models.

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From The Labs

Study seeks to identify biological markers that predict mesothelioma response to treatment

February 16, 2021 cancer treatment,  grant,  immune checkpoint,  Mesothelioma,  neoantigens,  Research

By taking a close look inside mesothelioma, Dr. B. Burt searches for clues to predict patient’s response to immunotherapy.

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From The Labs

Antibody response and ‘original antigenic sin’ in RSV influence vaccine development

February 11, 2021 COVID-19,  immunity to RSV,  Research,  RSV,  RSV antibodies,  vaccine development

Variation of human immune response to RSV reinfection suggests it is important to consider this variation in vaccine design.

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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