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From The Labs

What is the risk of excessive folic acid intake?

March 9, 2023 Birth defects,  folic acid,  Research,  spina bifida

Data in animal models support that folic acid supplementation should be restricted to an ideal benefit range.

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From The Labs

Researchers are making strides in the fight against gastroenteritis

March 7, 2023 cellular injury,  CLIC pathway,  gastroenteritis,  GII4,  human norovirus entry mechanism,  Norovirus,  Research

The findings provide insight into the viral infection process, highlighting unique pathways and targets for developing effective therapeutics.

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From The Labs

Cast your vote for Baylor College of Medicine in the STAT Madness Science Competition.

March 2, 2023 Research,  science competition,  STAT Madness

Support Baylor College of Medicine research. Vote to help these studies move up in the competition.

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From The Labs

Microbiome’s link to severe graft-versus-host disease suggests potential treatment

February 28, 2023 bone marrow transplant,  GVHD,  iron chelator,  microbiome,  oxygen,  Research

This is one of the first studies to provide an explanation and a potential solution for the imbalance in the gut microbiome that exacerbates GVHD.

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From The Labs

Metastatic cancer cells reveal potential vulnerabilities with implications for therapy

February 23, 2023 metastatic cancer,  molecular pathways,  molecular subtypes,  Research

This study identified molecular pathways that are common to many different metastatic cancers, regardless of tumor origin.

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From The Labs

How to compensate for loss of gene function? Think alternative splicing

February 21, 2023 alternative slicing,  gene duplication,  MBNL gene,  Myotonic Dystrophy Type 1,  paralog gene,  Research

Researchers uncovered new insights into a little studied biological mechanism that impacts Myotonic Dystrophy Type 1 severity and also is applicable to other diseases.

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From The Labs

Image of the Month: A transparent heart

February 17, 2023

From the Labs celebrates Heart Month with an image of a transparent mouse heart.

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From The Labs

Better understanding of craniofacial birth defects opens new roads for regenerative medicine

February 16, 2023 craniofacial development,  microRNA,  Research

The findings could lead to strategies to generate healthy cells to repair craniofacial defects in human patients.

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A person sitting on a dock at sunset with their knees pulled up to their head.
From The Labs

Altered gut microbiome and its products promote endometriosis in animal model

February 9, 2023 diagnostics,  endometriosis,  gut microbiome,  microbiome metabolites,  Research,  treatment

The findings open the door to explore novel therapies and diagnostic tools for this undertreated condition.

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A collage of microscopic images of different human cells.
From The Labs

Entanglement within a (transcriptional) bubble explains finely tuned regulation of gene expression

February 7, 2023 enhancer-promoter interactions,  entanglement,  gene expression,  Research,  transcriptional bubble

Researchers discovered that transcription of enhancers and promoters is interdependent and propose a mechanism to explain it.

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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