Understanding the cascade of molecular events leading to Rett syndrome
Characterizing the trajectory of molecular events leading to Rett syndrome opens new opportunities for novel therapeutic approaches.
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Rett Syndrome
Rett patients receive a new gene therapy treatment at Texas Children’s Hospital and Baylor College of Medicine
Nearly 25 years after the discovery that mutations in MECP2 gene cause Rett syndrome, the first gene therapy trial for this difficult-to-treat condition is underway.
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Deep brain stimulation induces more healthy neurons and sustained memory benefits in Rett animal models
DBS results in a significant and long-lasting improvement to memory in Rett animal models strongly suggesting evaluating this approach to treat Rett patients.
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National Postdoc Appreciation Week 2022
From the Labs celebrates National Postdoc Appreciation Week with a sample of the work conducted by Baylor postdocs.
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Dr. Huda Zoghbi named the 2022 Kavli Prize Laureate in neuroscience
Dr. Zoghbi is being recognized for two discoveries – ATAXIN1, the gene responsible for spinocerebellar ataxia 1, and MECP2, the gene responsible for Rett syndrome.
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Restoring long-term memory recall in a mouse model of Rett syndrome
Researchers have discovered that diminished memory recall in Rett syndrome mice can be restored by activating specific inhibitory cells in the hippocampus.
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Image of the Month: Training and neuronal activation in Rett mice
Early physical training triggers more dendritic arbors or cellular projections in hippocampal neurons (red), enhancing their functionality.
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Research opens new possibilities to improve the lives of girls with Rett syndrome
In a mouse model of Rett syndrome, early intensive training substantially delayed the appearance of symptoms and improved performance.
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Baylor College of Medicine faculty members elected fellows of the National Academy of Inventors
Drs. Mary K. Estes, Bert O’Malley and Huda Zoghbi of Baylor College of Medicine were three of the 148 renowned academic inventors named fellows of
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Future scientists inspired by recipients of Breakthrough Prize
Since being honored with the prestigious Breakthrough Prize in Life Sciences, Baylor College of Medicine’s Dr. Huda Zoghbi has been busy, but not just with
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