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A person holding a strand of their hair between their fingers.
From The Labs

Understanding the cascade of molecular events leading to Rett syndrome

December 19, 2024 gene expression dysregulation,  MECP2,  neurodevelopmental disorder,  Research,  Rett Syndrome

Characterizing the trajectory of molecular events leading to Rett syndrome opens new opportunities for novel therapeutic approaches.

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From The Labs

Rett patients receive a new gene therapy treatment at Texas Children’s Hospital and Baylor College of Medicine

December 12, 2023 clinical trial,  gene therapy,  NGN-401,  Research,  Rett Syndrome

Nearly 25 years after the discovery that mutations in MECP2 gene cause Rett syndrome, the first gene therapy trial for this difficult-to-treat condition is underway.

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From The Labs

Deep brain stimulation induces more healthy neurons and sustained memory benefits in Rett animal models

October 19, 2023 brain-derived neurotrophic factor,  deep brain stimulation,  MECP2,  Research,  Rett Syndrome

DBS results in a significant and long-lasting improvement to memory in Rett animal models strongly suggesting evaluating this approach to treat Rett patients.

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A collage of postdoc faces.
From The Labs

National Postdoc Appreciation Week 2022

September 22, 2022 12-h clock,  AI,  Alzheimer's,  Autism,  gene expression,  infantile spasm,  Postdoc appreciation week,  Research,  Rett Syndrome

From the Labs celebrates National Postdoc Appreciation Week with a sample of the work conducted by Baylor postdocs.

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From The Labs

Dr. Huda Zoghbi named the 2022 Kavli Prize Laureate in neuroscience

June 2, 2022 ataxia,  Kavli Prize in neuroscience,  Research,  Rett Syndrome

Dr. Zoghbi is being recognized for two discoveries – ATAXIN1, the gene responsible for spinocerebellar ataxia 1, and MECP2, the gene responsible for Rett syndrome.

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From The Labs

Restoring long-term memory recall in a mouse model of Rett syndrome

March 15, 2022 hippocampus,  long-term memory recall,  OLM cells,  Research,  Rett Syndrome,  SOM neurons

Researchers have discovered that diminished memory recall in Rett syndrome mice can be restored by activating specific inhibitory cells in the hippocampus.

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From The Labs

Image of the Month: Training and neuronal activation in Rett mice

April 1, 2021 mental and motor dissability,  neuronal arborization,  physical training,  Research,  Rett Syndrome

Early physical training triggers more dendritic arbors or cellular projections in hippocampal neurons (red), enhancing their functionality.

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From The Labs

Research opens new possibilities to improve the lives of girls with Rett syndrome

March 25, 2021 neuron arborization,  physical training,  Research,  Rett Syndrome

In a mouse model of Rett syndrome, early intensive training substantially delayed the appearance of symptoms and improved performance.

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From The Labs

Baylor College of Medicine faculty members elected fellows of the National Academy of Inventors

December 18, 2018 Alzheimer's,  Cancer,  NAI,  National Academy of Inventors,  Norovirus,  Research,  Rett Syndrome,  rotavirus

Drs. Mary K. Estes, Bert O’Malley and Huda Zoghbi of Baylor College of Medicine were three of the 148 renowned academic inventors named fellows of

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From The Labs

Future scientists inspired by recipients of Breakthrough Prize

January 6, 2017 Alzheimer's Disease,  Award,  Parkinson's Disease,  Rett Syndrome

Since being honored with the prestigious Breakthrough Prize in Life Sciences, Baylor College of Medicine’s Dr. Huda Zoghbi has been busy, but not just with

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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