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A model valentine-style heart sitting next to a stethoscope.
From The Labs

Gasdermin D emerges as a potential therapeutic target for atrial fibrillation

March 27, 2025 atria,  atrial fibrillation,  Dementia,  gasdermin D,  heart cells,  heart failure,  mitochondria,  reactive oxygen species,  Research,  Stroke

This study reveals that gasdermin D plays a novel role in the development of atrial fibrillation through multifaceted mechanisms.

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From The Labs

Machine learning assists in predicting risk of stroke

November 12, 2024 CF-LVAD,  congestive heart failure,  mitochondria,  OxPhos proteins,  Research,  SOAR,  Stroke

Machine learning could give physicians a means to anticipate complications and implement interventions before assist device implantation.

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From The Labs

GlyNAC reverses aging hallmarks in older adults

August 23, 2022 glutathione,  GlyNAC,  healthy aging,  mitochondria,  Research,  supplement

The first randomized clinical trial of GlyNAC supplementation showed that it improved a wide variety of age-associated deficiencies in older adults.

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From The Labs

Video of the Month: A cell dividing

April 5, 2022 cell division,  confocal microscopy,  mitochondria,  Poche lab,  Research,  science videos

Cell division is a highly dynamic and energy-demanding process.

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From The Labs

Image of the Month: The laboratory worm, C. elegans

March 2, 2021 Aging,  bacteria,  C. elegans,  Image of the month,  lipid signaling,  mitochondria,  Research

What is transparent, as long as a credit card is thick and helps solve science mysteries? The laboratory worm, C. elegans.

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From The Labs

A worm’s lessons for living a longer, healthier life

February 26, 2019 Aging,  C. elegans,  fat metabolism,  Longevity,  lysosomes,  metabolic signaling,  mitochondria,  oxidative tolerance,  Research,  sugar metabolism

Caenorhabditis elegans is a seemingly unimpressive worm. It is as long as a penny is thick, it lives in the soil feeding on microbes it

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From The Labs

Image of the Month: Mitochondria in human adipocytes

October 2, 2018 adipocytes,  Image of the month,  insulin resistance,  mitochondria,  Obesity,  Research,  type 2 diabetes

  In his lab at Baylor College of Medicine, Dr. Sean M. Hartig and his colleagues investigate novel ways to control obesity and type 2

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From The Labs

How disrupting mitochondria genes can lead to neurodegeneration

February 20, 2018 idh3a,  mitochondria,  Neurodegeneration,  neurological disease,  neurotransmission,  synapses

Years back, the Bellen lab identified many mutations in genes of the mitochondria, the energy generators of the cell. Among them was a mutation in

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From The Labs

A 12-hour biological clock coordinates essential bodily functions

August 31, 2017 12-hour biological clock,  Biological clocks,  circadian rhythm,  circatidal rhythm,  endoplasmic reticulum,  mitochondria,  Research

It’s not a good idea to disturb the circadian rhythm on a regular basis. For instance, experimental evidence shows that night-shift workers who periodically change

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From The Labs

A mouse model of human brown fat

August 3, 2017 adipocytes,  animal model,  Brown fat,  human brown fat,  metabolism,  mitochondria

When it gets cold around you, your body turns up the heat to maintain its normal temperature. The heat is produced by brown adipose tissue,

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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