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From The Labs

PBRM1’s new function supports a novel cancer-promoting mechanism

October 14, 2021 Cancer,  chromatin remodeler,  cytoskleleton remodeler,  genomic instability,  kidney cancer,  PBRM1,  Research,  SETD2,  tubulin methylation

New findings suggest that cancer-associated defects in chromatin remodeler genes can drive cancer by disrupting cytoskeletal activities.

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From The Labs

Identifying rare genetic variants that increase risk for lung cancer

March 18, 2021 ATM,  DNA damage,  DNA repair,  exome sequencing,  genomic instability,  lung cancer,  MLNR,  Pomc,  Research

Exome sequencing identified new variants that lead to higher levels of DNA damage, which increases the susceptibility for multiple cancers.

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From The Labs

Connecting Tau aggregates, transposable elements and neurodegeneration in Alzheimer’s disease

August 2, 2018 Alzheimer's Disease,  genomic instability,  neurlogic diseases,  Neurodegeneration,  Research,  tau,  transposable elements

Although it’s been known for years that the accumulation of Tau protein within brain cells in combination with progressive cell death is one of the

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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