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From The Labs

Uncovering unique features of early onset colorectal cancer in racial and ethnic minorities

February 13, 2025 Colorectal Cancer,  DNA methylation,  early onset colon cancer,  epigenetics,  racial and ethnic minorities,  Research

The findings bring hope and direction to better understand this emerging condition and support continuing these studies.

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From The Labs

Reviving immune responsiveness after tuberculosis

October 10, 2024 epigenetics,  everolimus,  immune weakness,  Research,  tricarboxylic acid cycle,  tuberculosis

The findings could reduce the illness and mortality that occur after TB has been successfully treated.

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From The Labs

CoRSIVs have been found in cattle. They offer a new approach to improve the livestock industry

August 20, 2024 cattle,  CoRSIVs,  epigenetics,  livestock,  mammalian genome,  Research

CoRSIVs provide information that may allow farmers to predict and select desirable cattle characteristics.

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From The Labs

Finding a food-cancer connection: How what you eat might affect your cancer risk

January 23, 2024 Colon Cancer,  diet and cancer risk,  early onset colon cancer,  epigenetics,  folate,  folate food fortification,  gene p16,  Research

This study reveals a mechanism by which the environment, diet in this case, can influence cancer risk.

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From The Labs

Researchers discover a vulnerability of acute myeloid leukemia

April 6, 2023 Acute myeloid leukemia,  AML,  epigenetics,  gene regulation,  PU.1,  Research,  SWI/SNF

Exploiting this vulnerability resulted in rapid tumor regression in animal models of AML.

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From The Labs

Breakthrough epigenetic study can improve the power to predict disease risk

January 31, 2023 CoRSIVs,  disease risk,  DNA methylation,  epigenetics,  epigenome-wide association study,  EWAS,  Research

The researchers hope their approach will have transformative effects in the field of epigenetic epidemiology.

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From The Labs

Scientists propose that obesity is a neurodevelopmental disorder

September 29, 2022 arcuate nucleus of the hypothalamus,  epigenetics,  food intake,  mouse neurodevelopment,  Obesity,  Research

The findings provide new evidence that developmental changes are likely involved in both early environmental and genetic influences on obesity risk.

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From The Labs

Unanticipated findings cast new light on the genetic regulation of different brain tumors

July 21, 2022 brain tumor,  ependymoma,  epigenetics,  EPN,  gene regulation,  HGG,  high-grade glioma,  Research,  SOX9,  tumor behavior

The findings highlight the importance of considering the mechanisms of gene regulation involved in different tumors when planning therapies.

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From The Labs

New method boosts the study of regulation of gene activity

June 30, 2022 DNA methylation,  epigenetics,  method,  NT-seq,  Research

The researchers report the development of a chemical-based sequencing method to quantify different epigenetic markers simultaneously.

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From The Labs

Tuberculosis induces premature cellular aging

March 24, 2022 cellular aging,  DNA methylation,  epigenetic clock,  epigenetics,  Research,  TB,  tuberculosis

It’s possible that premature cellular aging in TB is one reason why survivors have a three-fold increased risk of mortality.

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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