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From The Labs

CAR T cell therapy for pediatric brain cancer warrants further study

June 18, 2024 C7R,  CAR T cells,  clinical trial,  Glioma,  pediatric brain cancer,  Research

This study shows that this therapy can effectively get to the tumor, and the addition of C7R safely augments antitumor activity.

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From The Labs

Baylor College of Medicine researchers set the foundation for novel rare disease treatment

May 30, 2024 arginase deficiency,  clinical trial,  Medical Treatment,  rare disease,  Research

The story behind the discovery that led to the novel treatment revealed that scientific breakthroughs can sometimes happen in unexpected ways.

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From The Labs

CAR T cell therapy for T cell lymphoma shows promise in phase I trial

January 19, 2024 cancer therapy,  CAR Tcells,  CD5,  clinical trial,  Research,  T cell lymphoma

A first-in-human phase I clinical trial of patients with relapsed or refractory T cell lymphoma found early signals of anti-tumor efficacy and safety.

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From The Labs

Rett patients receive a new gene therapy treatment at Texas Children’s Hospital and Baylor College of Medicine

December 12, 2023 clinical trial,  gene therapy,  NGN-401,  Research,  Rett Syndrome

Nearly 25 years after the discovery that mutations in MECP2 gene cause Rett syndrome, the first gene therapy trial for this difficult-to-treat condition is underway.

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A graphic illustration of a family that appear as silhouettes filled with germs.
From The Labs

Can changing the gut microbiome alter the course of a disease?

October 24, 2023 bone marrow transplant,  butyrate,  clinical trial,  dietary intervention,  graft-versus-host disease,  gut microbiome,  potato starch,  Research

A simple, safe dietary intervention has an effect on the gut microbiome and metabolites in these patients.

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From The Labs

CAR NKT cells, a promising step forward in the treatment of solid tumors

November 10, 2020 CAR NK T cells,  clinical trial,  Immunotherapy,  neuroblastoma,  Research,  solid tumors

An ongoing clinical trial shows that human CAR NKT cells are safe and, in 1 of 3 patients, induced regression of metastatic lesions.

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From The Labs

ON A MATTER OF HEALTH: Clinical trial tests novel treatment strategy for ITP

October 8, 2019 bleeding,  blood clot,  clinical trial,  eltrombopag,  immune thrombocytopenia,  ITP

The immune system is meant to protect the body from foreign invaders. A rare condition called immune thrombocytopenia (ITP) occurs when the body’s defense system

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From The Labs

Orion shines a light in the dark for the blind

July 11, 2019 blindness,  clinical trial,  Orion device,  Research,  vision

In a dark room inside Baylor College of Medicine, study participants are asked to look at a blacked out computer screen and point to a

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From The Labs

From the labs to patent; osteoarthritis gene-therapy product is moving toward clinical trials

June 18, 2019 clinical trial,  gene therapy,  Il-1,  Osteoarthritis,  patent,  Research

More than 30 million people in the United States alone are affected by osteoarthritis (OA), a degenerative joint disease, and that number is expected to

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From The Labs

A new HER2 mutation leads to a clinical trial and to a promising diagnostic tool for metastatic breast cancer

July 27, 2017 circulating tumor DNA,  clinical trial,  HER2 gene,  Metastatic breast cancer,  neratinib

There is a group of metastatic breast cancers that has the HER2 gene amplified – the cells have many copies of it – which leads

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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