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From The Labs

Baylor College of Medicine Women in Science

February 11, 2022 Research,  Women in Science

From the Labs celebrates Baylor College of Medicine Women in Science!

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From The Labs

A closer look at genetic and cellular alterations involved in COPD

February 10, 2022 cell atlas,  cellular injury,  COPD,  inflammation,  lung fibrosis,  Research,  single cell RNA sequencing

Researchers contribute to a better understanding of the factors and processes involved in COPD.

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From The Labs

Wnt signaling is identified as a target in NEDAMSS disorder

February 8, 2022 CkIα,  IRF2BPL,  NEDAMSS,  neurological disorder,  Pits,  Research,  Wingless pathway,  Wnt/Wg

Research identifies an underlying mechanism and possible drug targets for NEDAMSS, a new severe neurological disorder in children.

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From The Labs

The circadian clock in heart failure

February 3, 2022 chronotherapy,  circadian clock,  fat metabolism,  heart failure,  obesity paradox,  Research,  Rev-erbα/β,  sugar metabolism

Disrupting the rhythm of molecular clock protein Rev-erbα/β leads to heart failure in animal models.

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From The Labs

Image of the Month: Molecular Hotspots

February 1, 2022 antibiotics,  binding affinity,  Research,  β-Lactamase,  β-Lactamase inhibitory proteins

Improved insight into molecular hotspots provides a better understanding of protein-protein interactions.

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From The Labs

Targeting MAPK4 may offer a new therapeutic opportunity for TNBC

January 27, 2022 AKT,  cancer therapy,  MAPK4,  PI3K,  PI3K inhibitor,  Research,  triple-negative breast cancer

MAPK4 seems to be involved in promoting triple-negative breast cancer growth and its resistance to certain therapies.

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From The Labs

Unraveling the complexity of vitamin B12 diseases

January 25, 2022 cblC,  cobalamin,  HCFC1,  MMACHC,  Research,  ribosome defect,  RONIN,  THAP11,  Vitamin B12,  Vitamin B12 genetic diseases

Vitamin B12 diseases involving RONIN (THAP11) and HCFC1 proteins are hybrid syndromes that affect both vitamin B12 and ribosome functions.

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From The Labs

From the Labs is calling for image and video submissions!

January 20, 2022 call for submissions,  Research,  research images,  research videos

From the Labs invites the research community at Baylor College of Medicine to submit their research images and videos.

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From The Labs

In memoriam of genetics pioneer Dr. C. Thomas Caskey

January 18, 2022 C. Thomas Caskey,  genetics pioneer,  human genetics. molecular genetics,  in memoriam,  Research

Dr. C. Thomas Caskey built the genetics program at Baylor from the ground up, founding and growing the Department of Molecular and Human Genetics into a national leader in the field.

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From The Labs

Alzheimer’s disease risk genes alter neuroprotective mechanism

January 13, 2022 ABCA1 agonist,  Alzheimer's Disease,  Alzheimer's genetic risk factors,  glia,  lipid droplets,  neuroprotection,  Research,  ROS

New insights into factors involved in Alzheimer’s disease support that multiple alterations at the genetic and other cellular levels combine to induce the disease.

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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