From The Labs Archives - Page 72 of 94 - Baylor College of Medicine Blog Network

CRKL in 22q11.2; a key gene that contributes to common birth defects

May 24, 2017 22q11.2, Birth defects, CRKL, cryptorchidism, DiGeorge syndrome, Genetics, genitourinary birth defects, hypospadias, kidney birth defects, mouse model

The 22q11.2 region of human chromosome 22 is a hotspot for a variety of birth defects. Scientists learned about this region because it is deleted in

From The Labs

Mouse blood vessels and immune system can team up against cancer metastasis

May 19, 2017 angiogenesis, anti-blood vessel therapy, Breast Cancer, Breast cancer microenvironment, Immunotherapy, Mouse models, T cells, vessel normalization

Picture a shapeless, small mass of tumor cells inside an otherwise healthy organ. The tumor is growing, thanks, among other things, to its ability to

From The Labs

Bacteria living in your gut may help diagnose colorectal cancer

May 15, 2017 colonoscopy, Colorectal Cancer, diagnostic test, gut microbiome, microbiome

Those millions of bacteria living in your gut may someday be your allies in early detection of colorectal cancer, the second-leading cause of cancer-associated death in

From The Labs

Mutated genes and rogue proteins can reveal new ways to treat breast cancer

May 10, 2017 Breast Cancer, breast tumor, mass spectrometry, personalized treatments, proteogenomics, tumor xenograft

Scientists are puzzled by mysteries such as, why a certain drug that induced one tumor to shrink in one patient did not affect the growth

From The Labs

Largest study of malignant brain tumors finds new genetic markers for two distinct glioma subtypes

May 5, 2017 brain tumor, genetic markers, Genetics, glioblastoma, Glioma

In 2017, approximately 24,000 people will be diagnosed with malignant brain tumors and 17,000 will die from the disease in the United States. The most

From The Labs

Of mice, men and proteasomes; OTUD6B variant causes intellectual and physical disability

May 3, 2017 developmental disorders, Human genetics, intellectual disabilities, Mouse models, OTUD6B, physical disabilities, proteasome, whole exome sequencing

One of Dr. Magdalena Walkiewicz’s patients had not received a genetic diagnosis for his condition that included a number of intellectual and physical disabilities. After

From The Labs

Image of the Month: Mouse brain with Batten disease

May 1, 2017 Juvenile Batten disease, lysosomal disorder, neurological disease, waste storage disorder

Juvenile Batten disease is one of nearly 50 human cellular waste storage disorders. In the Sardiello lab, researchers use genetics, cell biology and systems biology approaches

From The Labs

Changes in NLRP genes may be an answer to unexplained female infertility

April 28, 2017 Fertility, in vitro fertilization, infertility gene, mouse model, NLRP genes

Scientists estimate that as many as 15 percent of couples with infertility and 50 percent of women with recurrent pregnancy loss do not have a

From The Labs

Neurons deep in brain are more active than once thought

April 26, 2017 Cerebellum, cognitive process, granule cell, neuron, Neuroscience

It’s the part of the brain that makes sure you cannot tickle yourself. The cerebellum, an apple-sized region near the base of the skull, senses

From The Labs

From mouse model to human; serendipity leads to human genetic diagnosis

April 24, 2017 ATXN1-CIC, Autism, developmental delay, epilepsy, hyperactivity, intellectual disabilitis, Mouse models, Neuroscience

When Dr. Huda Zoghbi and her colleagues were investigating the role protein complex ATXN1-CIC plays in the normal development of the mouse brain they did not