From The Labs Archives - Page 21 of 93 - Baylor College of Medicine Blog Network

Innovative live high-resolution imaging and dynamic analysis enable the study of the mammalian heart at early developmental stages.

From The Labs

Changing the perspective on the origin of enzymatic catalytic power

July 28, 2022 artificial enzyme design, destabilization of ground states, enzymatic catalysis, noncovalent interactions, Research, stabilization of transition states, water

The findings have important implications not only to better understand the catalytic power of enzymes but also for practical drug design applications.

From The Labs

Researchers discover novel light-gated potassium channel

July 26, 2022 channelrhodopsins, light-gated ion channels, optogenetics, potassium channel, Research

A new class of light-gated channels promises to pave the way for rapid and efficient optical neuronal silencing.

From The Labs

Unanticipated findings cast new light on the genetic regulation of different brain tumors

July 21, 2022 brain tumor, ependymoma, epigenetics, EPN, gene regulation, HGG, high-grade glioma, Research, SOX9, tumor behavior

The findings highlight the importance of considering the mechanisms of gene regulation involved in different tumors when planning therapies.

From The Labs

Brain sphingolipid metabolism is closely involved in Gaucher disease

July 19, 2022 Gaucher disease, glia, glucosylceramide, lipid metabolism, lysosomes, neurodegenerative disease, neurons, Parkinson's Disease, Research, sphingolipid

Disruption of sphingolipid metabolism led to neurodegeneration in animal models, revealing a new molecular path to Gaucher’s disease.

From The Labs

Emu has improved the accuracy of bacterial identification

July 7, 2022 16S, bacterial identification, microbiome, next-generation sequencing, Research, rRNA

Emu can advance our understanding of the roles of the microbiome in water, soil and the intestinal tract.

From The Labs

Image of the Month: Neural tracts involved in speech recovery after stroke

July 5, 2022 Image of the month, neural paths, Research, speech, Stroke

This work helps predict the types of brain damage and behavior that lead to chronic language loss, thus informing both psychological theories and treatment approaches to language.

From The Labs

New method boosts the study of regulation of gene activity

June 30, 2022 DNA methylation, epigenetics, method, NT-seq, Research

The researchers report the development of a chemical-based sequencing method to quantify different epigenetic markers simultaneously.

From The Labs

Research opens the door to improved treatments for congenital heart disease

June 28, 2022 congenital heart disease, personalized therapy, Research, single-cell genomics, snRNA-seq

The first genomics analysis of congenital heart disease has improved our understanding of the mechanisms underlying the progression of the condition and revealed opportunities for personalized treatments.

From The Labs

A potentially more effective treatment for HER2 mutant metastatic breast cancer

June 23, 2022 Breast Cancer, cancer treatment, HER2 mutations, lobular breast cancer, Metastasis, neratinib, poziotinib, Research

A phase II clinical trial is on its way to assess the value of poziotinib in the treatment of this devastating condition.