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From The Labs

Unanticipated findings cast new light on the genetic regulation of different brain tumors

July 21, 2022 brain tumor,  ependymoma,  epigenetics,  EPN,  gene regulation,  HGG,  high-grade glioma,  Research,  SOX9,  tumor behavior

The findings highlight the importance of considering the mechanisms of gene regulation involved in different tumors when planning therapies.

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From The Labs

Sox9 reshapes the biliary tree in Alagille syndrome

October 10, 2019 Alagille syndrome,  bile,  bile tree,  cholestasis,  intrahepatic bile ducts,  JAG1,  liver,  Notch signaling,  Research,  SOX9

Alagille syndrome is a rare pediatric genetic disorder that can affect the liver, heart, kidneys, blood vessels, skeleton and other tissues. One major characteristic of

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From The Labs

No SOX9, no cartilage; and how DDRGK1 causes a rare human skeletal dysplasia

April 11, 2017 cartilage,  DDRGK1,  dwarfism,  Genetics,  SEMD,  Skeletal dysplasia,  SOX9

SEMD, Shohat-type spondyloepimetaphyseal dysplasia, is a rare type of skeletal dysplasia that affects the development of cartilage and results in a form of dwarfism with a

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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