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Policywise

Epic tools can increase racial/ethnic diversity in clinical research

August 2, 2024 Autism,  BPA,  Clinical research,  Clinical Trials,  diverse,  Diversity,  EPIC,  MyChart,  Research

A closer look at how BPA and MyChart have been instrumental in helping connect with a diverse patient population in clinical research.

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From The Labs

Dawn-to-dusk dry fasting could alleviate the health risks of individuals with an increased body mass index

July 31, 2024 BMI,  dawn-to-dusk fasting,  Diabetes,  heart disease,  Research

Dawn-to-dusk dry fasting helped reduce factors associated with risk for diabetes, heart disease and other complications.

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From The Labs

Congratulations, Dr. James R. Lupski, 2024 Mendel Lecturer and recipient of the Gilded Pea Award!

July 25, 2024 Gilded Pea award,  Human genetics,  human genomics,  Mendel lecture,  Rare Diseases,  Research

Dr. James R. Lupski has delivered more than 620 lectures in 37 countries, but none was received with nearly the same enthusiasm as his Mendel lecture this past June in Berlin.

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From The Labs

Defective serotonin 2C receptors lead to memory deficits in mice and humans

July 23, 2024 Alzheimer's Disease,  Memory,  Research,  serotonin 2C receptor

The findings not only provide new insight into the factors regulating healthy memory but also in conditions associated with memory loss, like Alzheimer’s disease.

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From The Labs

Image of the Month: The wooly mammoth emerges from the past

July 17, 2024 ancient DNA,  fossil chromosomes,  Research,  wooly mammoth

Researchers have peered into the chromosomes of the wooly mammoth, a magnificent creature that has been extinct for nearly 4,000 years.

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From The Labs

Cells with IFITM5 mutation get caught in a loop leading to osteogenesis imperfecta type V

July 11, 2024 bone stem cells,  IFITM5,  osteogenesis imperfecta,  Research

These findings not only inform on the mechanism of OI type V, they also facilitate the development of future therapies for this condition.

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From The Labs

Study opens new opportunities to develop cancer treatments

June 25, 2024 cancer datasets,  cancer treatment,  drug repurposing,  integrated computational analysis,  Research

The team integrated proteogenomic datasets of more than 1,000 tissue samples spanning 10 cancer types to illuminate protein targets for cancer therapy.

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From The Labs

CAR T cell therapy for pediatric brain cancer warrants further study

June 18, 2024 C7R,  CAR T cells,  clinical trial,  Glioma,  pediatric brain cancer,  Research

This study shows that this therapy can effectively get to the tumor, and the addition of C7R safely augments antitumor activity.

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From The Labs

A promising approach to develop a birth control pill for men

June 11, 2024 birth control pill,  CDD-2807,  male contraception,  Research,  sperm,  STK33

The novel strategy is sperm-specific, has minimal safety concerns and the effects are reversible in animal models.

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From The Labs

hnRNPM, a guardian of the integrity of cellular protein synthesis

June 6, 2024 Cancer,  cryptic splicing,  hnRNPM,  Interferon,  protein synthesis,  Pseudo splice sites,  Research

A connection with cancer cells suggests that hnRNPM may hold clinical promise.

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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