Image of the Month: Zika virus builds underground tunnels
This is the first time that tunneling has been shown by Zika virus infection in placental cells.
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Research
Long-term survival supports the potential benefit of CAR T cell therapy to treat solid tumors
An 18-year survivor of neuroblastoma is believed to represent the longest reported remission to date in a patient treated with chimeric antigen receptor (CAR) T cell therapy.
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Understanding the world within: study reveals new insights into phage–bacteria interactions in the gut microbiome
By evaluating temporal trends in the guts of developing children, this study helps to lay the groundwork for therapeutics and diagnostics leveraging the microbiome and its constituents.
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How MAGE-A4 helps tumors evade immune responses crucial for their elimination
The next step could include human clinical trials to test potential therapeutic avenues to restore the ability to fight the tumor.
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Rare chromosome reshuffling leads to severe complex form of epilepsy
Although it’s more commonly found in cancer, chromosome reshuffling is increasingly identified in neurodevelopmental disorders.
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Uncovering unique features of early onset colorectal cancer in racial and ethnic minorities
The findings bring hope and direction to better understand this emerging condition and support continuing these studies.
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Hear this – researchers are mapping the cells that tune in to sound
The findings challenge long-standing principles of hearing processing in the brain and offer fresh avenues for therapeutic exploration.
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Rotavirus protein NSP4 manipulates gastrointestinal disease severity
The findings suggest that regulating NSP4 could lead to new strategies to prevent or treat rotavirus infections.
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Sprinter and marathoner CAR T cells reveal their distinct cancer-killing behavior
The study lays a foundation for designing CAR molecules that maximize antitumor activity beyond B cell malignancies.
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Discovering replication hubs of human norovirus
The findings offer potential new targets for antivirals to treat this serious threat to children and immunocompromised patients.
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