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CDK4/6 inhibitor therapy

From The Labs

Interferon linked to ER+/HER- metastatic breast cancer resistance to therapy

March 12, 2021March 12, 2021CDK4/6 inhibitor therapy, endocrine therapy, ER+/HER2- breast cancer, Interferon, Metastatic breast cancer, Research, resistance to cancr treatment

Both preclinical models and tumor samples from patients with ER+/HER2- breast cancer link high IFN signaling to resistance to treatment.

From the Labs: Microscopy image of a brain region that coordinates survival adaptations to food shortages. Image courtesy of the authors/Cell Reports, 2021.