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From The Labs

Not just a ‘bad guy,’ Tau also plays a ‘good guy’ role protecting our brains

August 30, 2024 Alzheimer's Disease,  glia,  lipid droplets,  neuronal damage,  Research,  ROS,  tau

This study opens the door to potential new strategies to slow, reverse and treat neurodegenerative conditions.

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From The Labs

Alterations in human gene TRPC5 cause obesity and postpartum depression

August 29, 2024 Obesity,  postpartum depression,  Research,  TRPC5

TRPC5 acts on a brain region that regulates multiple innate behaviors including feeding, anxiety, socialization and maternal care.

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From The Labs

Gene splicing gone wrong leads to aggressive medulloblastoma

August 27, 2024 alternative splicing,  medulloblastoma,  OTX2,  pediatric brain cancer,  PPHLN1,  Research

Disturbing OTX2’s gene-splicing ability reduced tumor growth, opening possibilities for improved treatments.

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From The Labs

Baylor College of Medicine receives more than $17 million from CPRIT

August 22, 2024 Cancer,  CPRIT awards,  Research

The CPRIT awards support developmental research focusing on promising new insights into cancer treatment and innovative core facilities.

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From The Labs

CoRSIVs have been found in cattle. They offer a new approach to improve the livestock industry

August 20, 2024 cattle,  CoRSIVs,  epigenetics,  livestock,  mammalian genome,  Research

CoRSIVs provide information that may allow farmers to predict and select desirable cattle characteristics.

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From The Labs

TULIPs in brain tumors could be exploited therapeutically

August 15, 2024 brain tumor,  ependymoma,  histone methylation,  PFA,  Research,  TULIP,  tumor genome

TULIPs are 3D genome features in PFA ependymoma that are not present in other types of pediatric brain cancer.

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From The Labs

A neural biomarker to monitor OCD patient’s response to DBS

August 13, 2024 DBS,  neural signature,  OCD,  psychiatric disorders,  Research

The findings could help demystify the process and make the therapy more accessible to a greater number of clinicians and patients.

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From The Labs

A potential new therapeutic target for Group 3 medulloblastoma

August 8, 2024 CAR T cell,  grade3-medulloblastoma,  Immunotherapy,  pediatric brain cancer,  protogenin,  Research

Researchers identified and located a population of stem-like cells that initiates and maintains Group 3 medulloblastoma in the developing brain.

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From The Labs

Student-mentor pair receives prestigious HHMI Gilliam Fellowship

August 6, 2024 COVID,  HHMI Gillian Fellowship,  HIV,  placenta,  preeclampsia,  Research,  Women's Health,  zika

The HHMI Gilliam fellows are recognized for their outstanding research and commitment to advancing equity and inclusion in science.

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From The Labs

Dawn-to-dusk dry fasting could alleviate the health risks of individuals with an increased body mass index

July 31, 2024 BMI,  dawn-to-dusk fasting,  Diabetes,  heart disease,  Research

Dawn-to-dusk dry fasting helped reduce factors associated with risk for diabetes, heart disease and other complications.

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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