Ana Rodríguez, Author at Baylor College of Medicine Blog Network

The dark side of antibiotic ciprofloxacin

July 25, 2018 antibiotics, aorta tears and ruptures, aortic aneurysms and dissections, ciprofloxacin, extracellular matrix, fluoroquinolones, mouse model, Research

UPDATE: A few months after this article was posted, the work by Baylor researchers has begun to have international impact. Read the details here. The use

From The Labs

The genetic diversity in Africa is greater than in any other region in the world

July 19, 2018 Batswana, genetic diversity in Africa, HIV, Research

Looking at a subset of HIV-positive children from Botswana, an international team of researchers, co-led by scientists from Baylor College of Medicine, characterized the genetic

From The Labs

The lengths a cancer cell would go to survive

July 17, 2018 mRNA 3ʹUTR shortening, oncogenes, PTEN, Research, tumor formation, tumor suppressor genes

Oncogenes and tumor suppressor genes have long been implicated in tumor development. Oncogenes drive cells to grow faster and survive longer, while tumor suppressor genes

From The Labs

Sorting out what drives Huntington’s disease

July 12, 2018 fruit fly, high-throughput, huntingtin, Huntington’s disease, neurological disease, Research

Neurological diseases are typically associated with a multitude of molecular changes. But out of thousands of changes in gene expression, which ones are actually driving

From The Labs

Alternative splicing is crucial to muscle mass maintenance

July 10, 2018 Aging, alternative splicing, chronic disease, muscle mass maintenance, Rbfox1, Rbfox2, Research

Despite the importance that changes in muscle mass have in aging, overall body metabolism and in chronic disease, we still don’t fully understand the mechanisms

From The Labs

The Hippo pathway: tailor of the developing heart

July 5, 2018 blood vessels, heart development, heart growth, Hippo pathway, Research, single cell transcriptomics

The Hippo pathway is an inhibitor of adult heart regeneration; if you take the Hippo pathway away, then the heart can regenerate. But, can the

From The Labs

Image of the Month: ovarian cancer cells

July 3, 2018 Image of the month, ovarian cancer, Research, USP15

In her lab at Baylor College of Medicine, Dr. JoAnn Richards, Dr. Achuth Padmanabhan, instructor of molecular and cell biology and their colleagues are exploring new ways to

From The Labs

The Sixth Annual Michael E. DeBakey Department of Surgery Resident Research Day Symposium

June 28, 2018 Michael E. DeBakey Department of Surgery, Research, Surgery Resident Research Day

June 5-6, 2018 The Michael E. DeBakey Department of Surgery presents the Annual Resident Research Day Symposium to celebrate the accomplishments of its research program

From The Labs

There is more going on in DM1 than just alternative splicing

June 26, 2018 alternative splicing, AMPK-alpha, DM1, DMPK gene, myotonic dystrophy, PDGFR-beta, Research

Myotonic dystrophy type 1 (DM1) is the most common adult-onset muscular dystrophy that affects multiple organ systems. People with this condition develop progressive muscle wasting

From The Labs

Of fruit flies, genes and aortic aneurysms

June 21, 2018 aortic aneurysm, ari-1, fruit fly, parkin, Research

One of the goals of Dr. Hugo Bellen’s lab is to conduct genetic screens in the fruit fly to identify genes that cause neurodevelopmental and