From The Labs Archives - Page 14 of 96 - Baylor College of Medicine Blog Network

From The Labs

Neuron-glioblastoma conversations across the brain spark tumor invasion

August 10, 2023 brain tumor, glioblastoma, neuron, Research, SEMA4F, tumor infiltration

The findings suggest SEMA4F is an essential factor for glioma progression and neuronal activity-dependent infiltration.

Two slides showing breast cancer cells as blue or green dots on a blue background.

From The Labs

A potential strategy to control MAPK4-dependent cancer growth

August 8, 2023 AKT, cancer growth, lung cancer, MAPK4, PDK1, Prostate Cancer, Research, triple-negative breast cancer

This study has advanced our understanding of the molecular mechanisms underlying the tumor-promoting activity of MAPK4.

From The Labs

DNA tilts and stretches underlie differences in mutation rates across genomes

August 3, 2023 DNA 3D structure, mutation rate, Research, statistical model

DNA is much more than a linear sequence of building blocks; it has a 3D structure that carries important meaning,

From The Labs

Video of the Month: The Zebrafish Core

August 1, 2023 animal models, Core labs, Research, zebrafish

Join Dr. Daniel Gorelick and Lauren Marie Pandolfo on a tour of the Zebrafish Core highlighting its state-of-the-art facilities and research.

From The Labs

Serendipity reveals an opportunity to improve the success of chemotherapy in triple negative breast cancer

July 27, 2023 kinase inhibitor, KIPA, purine-binding protein, Research, TNBC, triple-negative breast cancer

Researchers identified a tumor protein signature that predicts chemotherapy sensitivity and favorable clinical outcomes.

The intersection of big data and genomics

From The Labs

A wide spectrum of human neurological diseases linked to variations of one gene, DHX9

July 25, 2023 DHX9, genetic diagnosis, Genome Sequencing, genomic variation, neurological disease, neuropathy, Research, undiagnosed disease

This study shows that gene DHX9 is involved in regulating mammalian neurodevelopment and neuronal well-being.

From The Labs

High-resolution map of the human placenta reveals COVID virus hideouts

July 20, 2023 COVID, human placenta, placental immune microenvironment, Pregnancy, Research, spatial transcriptomics

The researchers’ novel approach sheds light on the interactions between the COVID virus and the human placenta.

From The Labs

Drug decelerates bacterial race to antibiotic resistance

July 18, 2023 antibiotic resistance, bacterial infection, DEQ, mutations, Research, stress response

The researchers screened 1,120 drugs approved for human use for their ability to dial down the emergence of antibiotic resistance mutations and found a promising candidate.

From The Labs

Astrocytes: a hub for processing smell perception

July 13, 2023 astrocytes, GABA, neuronal activation, Research, sense of smell, serotonin, serotonin transporter Slc22a3

Researchers reveal a new mechanism that is required to maintain astrocyte-neuron communication and process smell perception.

From The Labs

Low-glucose sensor in the brain promotes blood glucose balance

July 11, 2023 anoctamin 4, blood glucose, glucose-excited neurons, glucose-inhibited neurons, ion channel, Research, type 1 diabetes

The findings suggest that glucose-sensing neurons in the brain are important for whole body glucose regulation, including during diabetes.