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From The Labs

Human mini guts reveal new insights into Cronkhite-Canada syndrome and potential new therapies

November 16, 2023 Cronkhite-Canada syndrome,  human intestinal organoids,  polyps,  Rare Diseases,  Research,  serotonin

The work also highlights the value of human organoid technology to improve the understanding of any disease and identify potential clinical applications.

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From The Labs

Astrocytes: a hub for processing smell perception

July 13, 2023 astrocytes,  GABA,  neuronal activation,  Research,  sense of smell,  serotonin,  serotonin transporter Slc22a3

Researchers reveal a new mechanism that is required to maintain astrocyte-neuron communication and process smell perception.

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From The Labs

Overactive brain circuit causes anorexia in animal model

May 12, 2022 anorexia,  brain circuit,  dopamine,  DRD1,  Research,  serotonin

Restoring the normal activity of a particular overactive brain circuit improved anorexia in an animal model of the condition.

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From The Labs

Eating for hunger or pleasure? This is how the brain handles these feeding behaviors

August 26, 2021 brain circuit,  GABA A receptor,  hunger,  ion channel,  Research,  serotonin,  serotonin 1B receptor,  serotonin 2C receptor

The researchers found that each type of feeding is wired by its own independent circuit that does not influence the other type.

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From The Labs

‘Can you hear me, now?’ A new strategy ‘raises the volume’ of hard-to-detect gut-body communication

June 27, 2019 enteroendocrine cells,  enteroids,  gut-body communication,  microbiome,  neurogenin-3,  Norovirus,  Research,  rotavirus,  serotonin

Throughout the gastrointestinal tract there are specialized hormone-producing cells called enteroendocrine cells and, although they comprise only a small population of the total cells, they

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From the Labs: Image of the Month

Blood vessels (magenta) intertwined with metastatic medulloblastoma tumor cells (green) nestled within the protective layers that surround the mouse spinal cord. From the Labs: a closer look at metastatic medulloblastoma

Healthy Habits: A DOC-umentary Series

https://www.youtube.com/watch?v=SlNiMWHUhbc

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